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Scientists at UC say restoring a brain protein, not removing amyloid plaques, should be the target. Experts estimate more than 6 million Americans are living with Alzheimer’s dementia. But a recent study, led by the University of Cincinnati, sheds new light on the disease and a highly debated new drug […]

COVID-19 pandemic is not over and it will not be over for quite some time. The only way we can bring the ending of it closer is by vaccinating. But for how long will these vaccines provide us the necessary protection? Scientists at UCL found that the total antibody levels […]

Fraser Island (K’gari) funnel web spider can bite and kill you. Sure, we now have strong anti-venoms, but it can be deadly. However, it can also be life-saving as scientists have developed a drug candidate from a molecule found in the venom of funnel web spiders. These drugs could one […]

Mammals have a poor ability to recover after a spinal cord injury which can result in paralysis. A main reason for this is the formation of a complex scar associated with chronic inflammation that produces a cellular microenvironment that blocks tissue repair. Now, a research team led by Leonor Saude, […]

Castration is known to extend life in male sheep. Researchers here show that epigenetic clocks constructed for this species show the expected slowing of epigenetic aging following castration. This is a way to dig deeper into the question of how it is that females live longer than males in mammalian […]

Scientists have completed the largest and most diverse genetic study of Type 1 diabetes ever undertaken, identifying new drug targets to treat a condition that affects 1.3 million American adults. Several potential drugs are already in the pipeline. Drugs targeting 12 genes identified in the diabetes study have been tested […]

University of Virginia School of Medicine researchers have discovered a previously unknown repair process in the brain that they hope could be harnessed and enhanced to treat seizure-related brain injuries. Common seizure-preventing drugs do not work for approximately a third of epilepsy patients, so new and better treatments for such […]

Some of the world’s most common allergy-inducing critters, from dust mites to fungi to shellfish, have one thing in common: chitin, the polymer that makes tough cell walls in mushrooms, fungal spores and crunchy lobster exoskeletons. A whiff of chitin triggers an immune response in the lungs, likely to prepare […]

CT scans for patients with concussions provide critical information about their risk for long-term impairment and potential to make a complete recovery – findings that underscore the need for physician follow-up. In a study led by UC San Francisco, researchers looked at the CT scans of 1,935 patients, ages 17 […]

In the largest study of its kind, an investigation by UC San Francisco has found no evidence that moderate coffee consumption can cause cardiac arrhythmia. In fact, each additional daily cup of coffee consumed among several hundred thousand individuals was associated with a 3 percent lower risk of any arrhythmia […]

New research adds to a body of evidence indicating decisions about withdrawing life-sustaining treatment for patients with moderate-to-severe traumatic brain injury (TBI) should not be made in the early days following the injury. In the study published in JAMA Neurology, researchers led by UC San Francisco, Medical College of Wisconsin […]

When we are exposed to a pathogen, the immune system’s B cells swarm to our lymph nodes, spleens, and tonsils. There, those cells mutate in germinal centers—microscopic boot camps that rush the B cells through volleys of mutations to produce the most potent antibodies for neutralizing the infectious agent. As […]

Developing drugs to combat tuberculosis, or TB, can be frustrating business. A gene essential to the bacteria’s lifecycle is discovered, scientists rush to develop drugs that inhibit the target, and then—disappointment. Volleys of compounds hurled at the essential gene target have little impact on microbial growth. The bacteria live on. […]

Unique development is biocompatible and does not require electricity, wires, or batteries. Tel Aviv University (TAU) researchers have developed a technology that involves a tiny sensor implanted in the nerve of an injured limb and is connected directly to a healthy nerve. Each time the limb touches an object, the sensor […]

The body’s so-called good cholesterol maybe even better than we realize. New research from Washington University School of Medicine in St. Louis suggests that one type of high-density lipoprotein (HDL) has a previously unknown role in protecting the liver from injury. This HDL protects the liver by blocking inflammatory signals […]

According to research supported by NIH's National Eye Institute, a form of gene therapy protects optic nerve cells and preserves vision in mouse models of glaucoma. The findings suggest a way forward for developing neuroprotective therapies for glaucoma, a leading cause of visual impairment and blindness. The report was published […]

Elevated levels of three specific circulating proteins are associated with protection against kidney failure in diabetes, according to new research from Harvard Medical School researchers at Joslin Diabetes Center published in Science Translational Medicine. “As well as acting as biomarkers for advancing kidney disease risk in diabetes, the proteins may also […]

Over the last decade, investigators at Beth Israel Deaconess Medical Center have been at the forefront of the effort to identify the small population of neurons deep within the brain that causes hunger. But precisely how these cells and the unpleasant feeling of hunger they cause actually drive an animal to […]