Related Science News

September 10, 2020

The genetics of blood: a global perspective

What’s the risk of different human populations to develop a disease? To find out, a team led by Université de Montréal professor Guillaume Lettre created an international consortium to study the blood of hundreds of thousands of people worldwide. In one of the largest studies of its kind, published in […]
September 9, 2020

New gene regulation model provides insight into brain development

A well-known protein family binds to many more RNA sequences than previously thought in order to help neurons grow. In every cell, RNA-binding proteins (RBPs) help tune gene expression and control biological processes by binding to RNA sequences. Researchers often assume that individual RBPs latch tightly to just one RNA […]
September 9, 2020

Research unravels what makes memories so detailed and enduring

In years to come, personal memories of the COVID-19 pandemic are likely to be etched in our minds with precision and clarity, distinct from other memories of 2020. The process which makes this possible has eluded scientists for many decades, but research led by the University of Bristol has made […]
September 8, 2020

How we sleep today may forecast when Alzheimer’s disease begins

What would you do if you knew how long you had until Alzheimer’s disease set in? Don’t despair. New UC Berkeley research suggests one defense against this virulent form of dementia — for which no treatment currently exists — is deep, restorative sleep, and plenty of it. Neuroscientists Matthew Walker […]
September 8, 2020

The brain can induce diabetes remission in rodents, but how?

In rodents with type 2 diabetes, a single surgical injection of a protein called fibroblast growth factor 1 can restore blood sugar levels to normal for weeks or months. Yet how this growth factor acts in the brain to generate this lasting benefit has been poorly understood. Clarifying how this […]
September 8, 2020

Seeing Progress

As we get older, many of our body’s processes start slowing down. For instance, a cut on the hand will take longer to heal after middle age than in youth. That said, it still heals. Unfortunately, this isn’t the case for the cells at the back of the eye, which […]
September 7, 2020

Dues forgetting a name or word mean that I have dementia?

The number of cases of dementia in the U.S. is rising as baby boomers age, raising questions for boomers themselves and also for their families, caregivers and society. Dementia, which is not technically a disease, but a term for impaired ability to think, remember or make decisions, is one of […]
September 7, 2020

Researchers offer insights into aging

What determines the life span of a mouse, alligator, dog or human? A team of scientists at the University of Georgia believes they have new insight into this age-old question. Emily Bertucci and Benjamin B. Parrott, a research team at the Odum School of Ecology and the Savannah River Ecology Laboratory, […]
September 7, 2020

Researchers find a cause and possible treatment for Fragile X

Yale scientists have discovered an underlying mechanism for Fragile X syndrome — a leading cause of autism and the primary genetic driver of intellectual disability — as well as a drug that reversed the underlying abnormality and autism-like behaviours in mice. Their research appears in the edition of the journal […]
September 7, 2020

Hearing loss may be a contributing factor to Alzheimer's disease

Aging is something we all have to deal with. And it’s no fun – your body gradually loses some of its capacities and you’re left wondering what you will be able to do tomorrow. One of the parts of aging is losing senses – older people tend to have impaired […]
September 6, 2020

You may be genetically predisposed to use illicit drugs

Some people are into the sort of behaviour that we know is harmful. For example, millions and millions of people drink, use illicit drugs, smoke, gamble and so on. You may be one of those people. But why? This new study, led by scientists from UCL, found that these harmful […]
September 4, 2020

Agreement tackles Alzheimer’s disease

Cardiff University has signed an agreement with Cytox to help the company develop a genetic risk assessment tool for Alzheimer’s disease. Under the licence, Oxford- and Manchester-based Cytox will access the University’s intellectual property (IP) regarding polygenic risk scoring algorithms for predicting the future onset of Alzheimer’s disease. Cytox will […]
September 3, 2020

Engineers reprogram yeast cells to become microscopic drug factories

By genetically reprogramming the cellular machinery of yeast they created microscopic factories that convert sugars and amino acids into plant-based drugs. Since antiquity, cultures on nearly every continent have discovered that certain plant leaves, when chewed or brewed or rubbed on the body, could relieve diverse ailments, inspire hallucinations or, […]
September 3, 2020

New Connections Reveal How Cancer Evades the Immune System

If cancer is a series of puzzles, new study pieces together how several of those puzzles connect to form a bigger picture. One major piece is the immune system and the question of why certain immune cells stop doing their job. Another piece involves how histones are altered within immune […]
September 3, 2020

How mechanical forces nudge tumors toward malignancy

All cancers are the result of cells that have gone haywire, multiplying out of control and expanding beyond their normal constraints. But not all tumors are the same: for reasons that remain poorly understood, some are more likely to become aggressive and metastasize to other parts of the body. New […]
September 2, 2020

Scientists Develop First Drug-Like Compounds to Inhibit Elusive Cancer-Linked Enzymes

A team of scientists from the University of Michigan Rogel Cancer Center has developed the first drug-like compounds to inhibit a key family of enzymes whose malfunction is associated with several types of cancer, including an aggressive form of childhood leukaemia. The enzymes — known as the nuclear receptor-binding SET domain […]
September 2, 2020

Mosaic ImmunoEngineering Inc. signs license-option to advance novel immunotherapy to treat cancer and infectious diseases

Mosaic ImmunoEngineering Inc., a private biotechnology company based in Novato, California, has signed a two-year option agreement with Case Western Reserve University and Dartmouth College, granting the company the exclusive right to license the technology for a novel platform technology using virus-like nanoparticles (“VLP”) to treat and prevent cancer and […]
September 2, 2020

Tiny tweezer developed at Vanderbilt can trap molecules on a nanoscale, creating powerful research capabilities into cancer metastasis, neurodegenerative diseases

In 2018, one-half of the Nobel Prize was awarded to Arthur Ashkin, the physicist who developed optical tweezers, the use of a tightly focused laser beam to isolate and move micron-scale objects (the size of red blood cells). Now Justus Ndukaife, assistant professor of electrical engineering at Vanderbilt University, has developed the […]
September 2, 2020

Handgrip strength shown to identify people at high risk of type 2 diabetes

A simple test such as the strength of your handgrip could be used as a quick, low-cost screening tool to help healthcare professionals identify patients at risk of type 2 diabetes. In new research, scientists at the universities of Bristol and Eastern Finland measured the muscular handgrip strength of 776 […]
September 2, 2020

Swine flu vaccination in pregnant women did not increase risk of autism in offspring

Two recent studies were unable to rule out that H1N1 (“swine flu”) vaccination (“Pandemrix”) and seasonal influenza vaccination given to pregnant women might be associated with autism spectrum disorder in the offspring. Now, a large study by researchers at Karolinska Institutet in Sweden, published in the journal Annals of Internal […]
September 2, 2020

Narcolepsy drug did not increase risk of fetal malformation

Modafinil is used to treat conditions such as narcolepsy. Reports have associated the drug with an increased risk of malformation in babies born to mothers who had taken it while pregnant. Now, a large registry study involving over two million pregnant women in Sweden and Norway shows that there is […]
September 2, 2020

Big Step in Regenerative Medicine

New stem cell technique offers hope for those with corneal damage. Harvard Medical School surgeons at Massachusetts Eye and Ear have replaced the ocular surface of four patients who each experienced chemical burns to one eye. The technique, cultivated autologous limbal epithelial cell transplantation (CALEC), uses stem cells taken from […]
September 2, 2020

Study Sheds Light on Survival Mechanism Activated by the Brain in Conditions of Uncertainty

Findings are relevant to an understanding of the neural mechanisms present in mental disorders such as post-traumatic stress disorder and addiction. A new Tel Aviv University study examined the brain's reactions in conditions of uncertainty and stressful conflict in an environment of risks and opportunities. The researchers identified the areas of the […]
September 2, 2020

Different responses in individual cells give muscles more control

Minute differences in individual muscle cell contractions allow the entire muscle to flex with greater control and accuracy. Long dismissed as “noise” or error, experts now suspect that biological systems may have evolved to include unavoidable variation as a form of information in their communication channels. A team of experts […]
September 2, 2020

To Treat Frontotemporal Dementia, Treat the Brain’s Immune Cells

The neurodegenerative disease known as frontotemporal dementia (FTD) causes untold suffering. As neurons die in regions of the brain important for maintaining our personalities and living a purposeful life, patients experience steadily worsening cognitive and behavioural symptoms, and the disease is generally fatal within a decade of diagnosis. Though FTD […]
September 2, 2020

Altered enzyme offers hope for spinal injury and stroke

An enzyme proven to help regrow damaged nerve tissue in animals but too unstable for use in humans has been redesigned for stability in research co-led by Marian Hettiaratchi of the Phil and Penny Knight Campus for Accelerating Scientific Impact at the University of Oregon. With stability added, the enzyme […]
September 2, 2020

Global collaboration needed to regulate embryo and embryoid research

The world’s scientific community must engage with a broad range of stakeholders to develop guidelines on embryo and embryoid research, according to a new paper from Rice University’s Baker Institute for Public Policy. Human embryo and embryoid research have expanded in recent years due to technological advances. But inconsistent or ambiguous restrictions […]
September 1, 2020

Genetic mutations may be linked to infertility, early menopause

A new study from Washington University School of Medicine in St. Louis identifies a specific gene’s previously unknown role infertility. When the gene is missing in fruit flies, roundworms, zebrafish and mice, the animals are infertile or lose their fertility unusually early but appear otherwise healthy. Analyzing genetic data in […]