Related Science News

October 18, 2017

Cancer slows but can’t stop a UO discovery on protein motion

A discovery in Marina Guenza's UO chemistry lab, published in a major physics journal, is already being tapped by outside scientists working on a new medical treatment for tuberculosis. The UO research, however, included a detour. Jeremy Copperman, a doctoral student leading it, was diagnosed with Hodgkin's lymphoma in the final year […]
October 17, 2017

UB spinoff company For-Robin moves one step closer to human clinical trials

Scientists from For-Robin Inc., a University at Buffalo biotechnology spinoff, have published new research results showing that the company’s cancer-fighting antibody can target, penetrate and kill human tumor cells effectively. The findings, reported in September in the journal Neoplasia, bring the company one step closer to human clinical trials. “This is a […]
October 17, 2017

For Older Adults, Volunteering Could Improve Brain Function

Older adults worried about losing their cognitive functions could consider volunteering as a potential boost, according to a University of Missouri researcher. While volunteering and its associations with physical health are well known, less has been known about its associations with mental functioning. Now, Christine Proulx, an associate professor in the Human […]
October 17, 2017

Childhood poverty, poor support may drive up pregnant woman’s biological age

Pregnant women who had low socioeconomic status during childhood and who have poor family social support appear to prematurely age on a cellular level, potentially raising the risk for complications, a new study has found. Researchers at The Ohio State University examined blood from pregnant women to evaluate the length […]
October 13, 2017

Bioengineering Fate

Using human induced pluripotent stem cells (iPSCs), a Harvard Medical School research team has bioengineered functional small intestine segments that, when implanted into rats, were capable of delivering nutrients into the bloodstream. The investigators describe their accomplishment in the online journal Nature Communications. Get more HMS news here. “In this study […]
October 13, 2017

NIH partners with 11 leading biopharmaceutical companies to accelerate the development of new cancer immunotherapy strategies for more patients

The National Institutes of Health and 11 leading biopharmaceutical companies today launched the Partnership for Accelerating Cancer Therapies (PACT), a five-year public-private research collaboration totaling $215 million as part of the Cancer Moonshot.  PACT will initially focus on efforts to identify, develop and validate robust biomarkers — standardized biological markers […]
October 13, 2017

Brain tumor treatment for dogs may soon be used in human patients

Data from a clinical trial at the Virginia-Maryland College of Veterinary Medicine at Virginia Tech to treat brain tumors in dogs may eventually be used to help humans. The study is trying to determine the safety of a new chemotherapeutic drug and drug delivery method in the treatment of brain tumors in dogs. It’s […]
October 13, 2017

Cholesterol byproduct hijacks immune cells, lets breast cancer spread

High cholesterol levels have been associated with breast cancer spreading to other sites in the body, but doctors and researchers don’t know the cause for the link. A new study by University of Illinois researchers found that the culprit is a byproduct of cholesterol metabolism that acts on specific immune cells so […]
October 13, 2017

Crystallizing discovery on a key target for cancer drugs

Many approved cancer therapies target a protein called epidermal growth factor receptor (EGFR) that regulates many crucial cellular processes and can speed the proliferation of tumor cells. Yale Cancer Center scientists now have made a fundamental discovery about EGFR signaling, reported in the journal Cell, that may open the potential for new types […]
October 13, 2017

New findings explain how UV rays trigger skin cancer

Melanoma, a cancer of skin pigment cells called melanocytes, will strike an estimated 87,110 people in the U.S. in 2017, according to the Centers for Disease Control and Prevention. A fraction of those melanomas come from pre-existing moles, but the majority of them come from sources unknown – until now. […]
October 11, 2017

New use for alcohol aversion drug in treatment of chemo resistant lung cancer

Scientists have had positive results from a laboratory-based study using a well-known alcohol aversion drug to try to combat chemotherapy resistance in the most common type of lung cancer, non-small cell lung cancer (NSCLC). The findings from the scientists at Trinity College Dublin and St James’s Hospital have been published […]
October 11, 2017

Discovery of rogue messengers that hinder body’s immune response to cancer

Researchers from Trinity College Dublin have made a discovery around treatment-resistant breast cancer that may turn the phrase, ‘don’t shoot the messenger’, on its head. The scientists have found that cell to cell messengers released by cancer cells which are not responding to treatment, can negatively affect the body’s immune […]
October 11, 2017

Scientists reveal how inflammation affects the life of brain cells

New King’s College London research reveals how blood inflammation affects the birth and death of brain cells, which could offer new treatment targets for antidepressants. Mounting evidence points to high levels of inflammation as an important biological abnormality leading to depression in at least one third of patients. However, this […]
October 10, 2017

Combination treatment targeting glucose in advanced brain cancer shows promising results in preclinical study

UCLA scientists have discovered a potential combination treatment for glioblastoma, the deadliest form of brain cancer in adults. The three-year study led by David Nathanson, a member of UCLA’s Jonsson Comprehensive Cancer Center, found that the drug combination tested in mice disrupts and exploits glucose intake, essentially cutting off the […]
October 10, 2017

Liquid Biopsy May Be New Way to Detect Liver Cancer Earlier, Easier

An international team of researchers at University of California San Diego School of Medicine and Moores Cancer Center, with colleagues at Sun Yet-sun University Cancer Center and other collaborating institutions, have developed a new diagnostic and prognosis method for early detection of hepatocellular carcinoma (HCC), based on a simple blood […]
October 9, 2017

DNA damage caused by cancer treatment reversed by ZATT protein

  An international team led by scientists at the National Institutes of Health is the first to discover a new way that cells fix an important and dangerous type of DNA damage known as a DNA-protein crosslink (DPC). The researchers found that a protein named ZATT can eliminate DPCs with […]
October 5, 2017

Diamonds track cancer

You would not expect diamonds to have anything to do with cancer treatment. But they can actually they improve patients’ chances of survival. “Using traditional techniques, it’s almost impossible to determine whether a cancer treatment has been 100 per cent or 99.9 per cent effective. The difference can have major […]
October 4, 2017

Tracking the body’s mini-shuttles

A team of researchers at Cardiff University’s Schools of Pharmacy and Pharmaceutical Sciences, Medicine, and Biosciences, together with the Basque Foundation for Science in Spain, has discovered a new way of tagging these nanobodies that are made naturally by cells. Exosomes play an important role in the way in which […]
October 4, 2017

Worm study reveals role of stem cells in cancer

Researchers from the Aboobaker lab in the Department of Zoology used the worms (planarians) which are known for their ability to regenerate their tissues and organs repeatedly. This process is enabled by their stem cells, which constantly divide to make new cells. Cell migration – or the movement of cells […]
October 4, 2017

Large, crystalline lipid scaffolds bring new possibilities to protein, drug research

Proteins and drugs are often attached to lipids to promote crystallization or ensure delivery to targeted tissues within the body, but only the smallest proteins and molecules fit within these fat structures. A new study reveals a lipid structure that can support much larger proteins and molecules than before, potentially […]
October 4, 2017

New method to measure cell stiffness could lead to improved cancer treatments

UCLA biophysicists have developed a new method to rapidly determine a single cell’s stiffness and size — which could ultimately lead to improved treatments for cancer and other diseases. The method allows researchers to make standardized measurements of single cells, determine each cell’s stiffness and assign it a number, generally […]
October 4, 2017

Study Will Explore Link Between HIV, Micro-Strokes, and Dementia

New research will seek to understand why people who are HIV positive are more susceptible to a progressive cerebrovascular disease that can ultimately give rise to dementia.  One of the goals of the research is to identify new ways to prevent the blockages that occur in blood vessels and cause […]
October 2, 2017

Dying cancer cells: Back From the Brink

A new collaboration between two UC Santa Barbara labs explores the underlying molecular mechanism of a remarkable process called anastasis, a Greek word meaning “rising to life.” Building on earlier work showing that cells can recover from the brink of death, the new study demonstrates that anastasis is an active […]
October 2, 2017

Research shines light on circadian clock in our muscles

Biological clocks are ticking everywhere throughout our body. They trigger the release of the hormone melatonin during sleep, leading to the secretion of digestive enzymes at lunchtime or keep us awake at the busiest moments of the day. A “master clock” in the brain synchronises all the subsidiary ones in […]
October 2, 2017

New drug to supercharge immune cells in the fight against cancer

A new cancer treatment with the ability to normalise tumour blood vessels and boost the body’s immune system has been developed by researchers from The University of Western Australia and the Harry Perkins Institute of Medical Research. Many tumours can become resistant to the body’s immune system by creating a […]
October 2, 2017

DNA Mutations Shed in Blood Predicts Response to Immunotherapy in Patients with Cancer

In a first-of-its-kind study, University of California San Diego School of Medicine researchers report that a blood sample, or liquid biopsy, can reveal which patients will respond to checkpoint inhibitor-based immunotherapies. “We can help predict response to immunotherapy by measuring the number of mutations in circulating tumor DNA using a […]
September 29, 2017

Battling belly fat: Specialized immune cells impair metabolism in aging

In a new study, Yale researchers have described how nervous systems and immune systems talk to each other to control metabolism and inflammation. Their finding furthers scientists’ understanding of why older adults fail to burn stored belly fat, which raises the risk of chronic disease. The study also points to […]
September 29, 2017

How to Grow a Spine

Like a string of pearls, the spine is made of a series of similar vertebrae. A so-called segmentation clock creates this repetitive arrangement in developing embryos: Each time the clock ticks, a vertebra starts to form. In a paper published Sept. 21 in Cell, Harvard Medical School genetics professor Olivier Pourquié—whose lab […]