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Case Western Reserve University researchers studying prions—misfolded proteins that cause lethal incurable diseases—have identified for the first time surface features of human prions responsible for their replication in the brain. The ultimate goal of the research is to help design a strategy to stop prion disease in humans—and, ultimately, to […]

University of Utah Health scientists and collaborators with the Adolescent Brain Cognitive Development (ABCD) Consortium have developed a rich resource for studying how the brain changes and matures during adolescence: a collection of functional MRI scans revealed patterns of brain activity in more than 6,000 9- and 10-year-old children. The […]

Evolution is hardly predictable. But it works. And works so well, that this efficiency of evolving is often underestimated by a large part of scientific community. Quick fact: in less than two weeks bacteria can evolve to resist antibiotics thousands of times stronger than what would have killed them at […]

A large international study on the effects of cooling the brain after a cardiac arrest shows that contrary to current treatment recommendations, it doesn’t actually improve survival or recovery. The study, published in the New England Journal of Medicine, suggests that a less intensive approach to temperature control in these patients […]

Christina often struggled to get through the average day. A former teacher diagnosed with treatment-resistant depression – along with OCD, bipolar disorder and Complex Post-Traumatic Stress Disorder (CPTSD) – was unable to work. At one point she was taking almost 60 different pills per day, with little to no effect […]

Altering traumatic memories in a way that eases their burden could be the key to treating survivors of post-traumatic stress disorder and other anxiety disorders, according to one of the University of Alberta’s newest Canada Research Chairs (CRC). Peggy St. Jacques, the psychology researcher in the Faculty of Science and CRC in […]

The B.1.1.7 coronavirus variant—also known as Alpha—may be more infectious because it contains mutations that make it better adapted to foil the innate immune system, at least for long enough to allow the virus to replicate and potentially find new hosts, according to a new study on BioRxiv. In the study, […]

New research published challenges a popular belief that intermittent fasting diets such as alternate day fasting or the ‘5:2’ are the most effective ways to lose weight. Over recent years, diets that see people fast on a few days each week have increased in popularity, reinforced by images of people’s […]

Researchers at Karolinska Institutet found industrial chemicals in the organs of fetuses conceived decades after many countries had banned the substances. In a study published in the journal Chemosphere, the researchers urge decision-makers to consider the combined impact of the mix of chemicals that accumulate in people and nature. “These […]

In a study published in Nature Communications, researchers at Karolinska Institutet provide insight into the sequence of events leading to the formation of functional mitoribosomes and sheds light on the mechanism of action of nine mitoribosome assembly factors involved in this process. The results may help yield novel opportunities for […]

Case Comprehensive Cancer Center, a partnership of Case Western Reserve University, University Hospitals and Cleveland Clinic, has joined with 71 other National Cancer Institute (NCI)-designated cancer centers and partner organizations to issue a joint statement urging the nation’s physicians, parents and young adults to get the human papillomavirus (HPV) vaccination back on […]

Researchers at the National Eye Institute (NEI) have determined how certain short protein fragments, called peptides, can protect neuronal cells found in the light-sensing retina layer at the back of the eye. The peptides might someday be used to treat degenerative retinal diseases, such as age-related macular degeneration (AMD). The […]

Medulloblastoma is a rare but devastating childhood brain cancer. This cancer can spread through the spinal fluid and be deposited elsewhere in the brain or spine. Radiation therapy to the whole brain and spine followed by an extra radiation dose to the back of the brain prevents this spread and […]

The intestinal disease necrotizing enterocolitis is a leading cause of death among premature infants born in the U.S. and across the globe. Characterized by excessive inflammation that can cause tissue decay in the bowels, the disease provides a pathway for infectious and deadly bacteria to enter the bloodstream. Despite four […]

The prevalence of genetic mutations associated with breast cancer in Black and white women is the same, according to a new JAMA Oncology study of nearly 30,000 patients led by researchers in the Basser Center for BRCA at the Abramson Cancer Center. About five percent of both Black and white women have a genetic mutation […]

Human babies do even more than we thought while sleeping. A new study from University of Iowa researchers provides further insights into the coordination that takes place between infants’ brains and bodies as they sleep. The Iowa researchers have for years studied infants’ twitching movements during REM sleep and how those twitches […]

A Rice University professor involved in the search for a way to treat and perhaps cure sickle cell disease is available to comment on a major advance revealed today in Science Translational Medicine. Rice University bioengineer Gang Bao is a pioneer in sickle cell research and a co-author of the breakthrough study released led […]

According to the Centers for Disease Control and Prevention, breast cancer ranks as the most prevalent cancer among American women. For over 40 years, mammography was the standard of care for breast cancer screening and detection but recently the popularity and use of digital breast tomosynthesis (DBT), or 3D mammography, […]

Adults who skip breakfast are likely to miss out on key nutrients that are most abundant in the foods that make up morning meals, a new study suggests. An analysis of data on more than 30,000 American adults showed that skipping breakfast – and missing out on the calcium in […]

High blood lipids and inactivity are two risk factors for atherosclerosis in humans. When the European brown bear (Ursus arctos) hibernates during winter, it is inactive for 5-6 months and also develops high blood lipids, but still show no signs of atherosclerosis. Professor Johan Frostegård´s research group at the Institute of […]

There’s a pill for many ailments, but ageing isn’t one of them. And while some mounting difficulty in thinking and processing is expected as you grow older, cognition experts say you can take steps to slow it down, no prescription required. Benjamin Hampstead, PhD, recently explained what we know about […]

Chatbots hold promise for dementia patient or caregiver support, but are still in their infancy, finds a paper published in the Journal of Medical Internet Research. None of the interactive digital apps tested by medical researchers and a computer scientist performed well on all testing criteria, and all the apps […]

University of Utah Health scientists and collaborators with the Adolescent Brain Cognitive Development (ABCD) Consortium have developed a rich resource for studying how the brain changes and matures during adolescence: a collection of functional MRI scans revealed patterns of brain activity in more than 6,000 nine- and ten-year-old children. The […]

Scientists are developing virus-sized robots that could defuse blood clots, explore human cells or even scrub water of impurities. But as these inventions get smaller, the laws of motion that govern these machines are not very intuitive, so researchers are drawing inspiration from nature, says Brad Nelson, professor of robotics […]

Researchers at the University of Virginia School of Medicine have taken a new approach to understanding how our genes determine the strength of our bones, allowing them to identify several genes not previously known to influence bone density and, ultimately, our risk of fracture. The work offers important insights into […]

Nearly 3,000 Canadians are living with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease or Charcot's disease. Each year, close to 1,000 people are diagnosed with ALS and as many will die from it. ALS is an incurable neurodegenerative disorder characterized by the selective loss of motor neurons. […]

Scientists at UC Santa Barbara, University of Southern California (USC), and the biotechnology company Regenerative Patch Technologies LLC (RPT) have reported new methodology for the preservation of RPT’s stem cell-based therapy for age-related macular degeneration (AMD). The new research, recently published in Scientific Reports(link is external), optimizes the conditions to cryopreserve, […]

Treatment options for a deadly liver cancer, fibrolamellar carcinoma, are severely lacking. Drugs that work on other liver cancers are not effective, and although progress has been made in identifying the specific genes involved in driving the growth of fibrolamellar tumors, these findings have yet to translate into any treatment. […]

The term “doomscrolling” describes the act of endlessly scrolling through bad news on social media and reading every worrisome tidbit that pops up, a habit that unfortunately seems to have become common during the COVID-19 pandemic. The biology of our brains may play a role in that. Researchers at Washington […]

Children growing up with HIV infection have concerning deficits in skeletal strength which become more apparent towards the end of pubertal growth, finds the largest study to date to investigate the link between HIV and skeletal health in children. The study, conducted in Zimbabwe and published in The Lancet Child […]