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Hydrogels are often used as drug delivery systems, but to be effective carriers for anti-cancer drugs, they need to be responsive to varied stimuli in the tumor microenvironment. Now, scientists from Japan have developed novel hydrogels to effectively deliver drugs to tumor sites in response to temperature and pH changes […]

Imagine experiencing chronic pain or depression so severe that no medication will bring relief. Such conditions may not be common, but they do exist. For patients fortunate enough to receive professional help, treatment often involves a combination of different therapies. One of these is transcranial magnetic stimulation (TMS). The thought […]

Heart problems cause disturbed gene activity in the brain’s memory center, from which cognitive deficits arise. Researchers at the German Center for Neurodegenerative Diseases (DZNE), the University Medical Center Göttingen (UMG) and the German Center for Cardiovascular Research (DZHK) come to this conclusion based on laboratory studies. They consider that […]

Major boost in COVID-19 antibodies seen in breast milk after vaccination. Nursing mothers who receive a COVID-19 vaccine may pass protective antibodies to their babies through breast milk for at least 80 days following vaccination, suggests new research from Washington University School of Medicine in St. Louis. “Our study showed […]

Scientists train deep learning algorithms to classify breast lesions from ultrasound images in a large multi-center study. In 2020, the International Agency for Research on Cancer of the World Health Organization stated that breast cancer accounts for most cancer morbidities and mortalities in women worldwide. This alarming statistic not only […]

Researchers from the University of Minnesota Twin Cities College of Science and Engineering and Medical School have developed a unique head-mounted mini-microscope device that allows them to image complex brain functions of freely moving mice in real-time over a period of more than 300 days. The device, known as the […]

At a cost of $38 billion a year, an estimated 5.3 million people are living with a permanent disability related to traumatic brain injury in the United States today, according to the Centers for Disease Control and Prevention. The physical, mental and financial toll of a TBI can be enormous, but […]

A study led by researchers at the Keck Graduate Institute (KGI), UC Berkeley and Vilnius University demonstrated new disease-detection capabilities of a hand-held device based on CRISPR gene-editing technology, a development that could lead to faster, portable genetic testing for diagnostics and research. Scientists look to variations at a single […]

Baby’s first words are a huge milestone in a child's development. It is one of those things that parents always remember. However, when a baby says his or her first words, it is not actually the beginning of the language skills development. Scientists at the University of Edinburgh found that […]

During a world first therapy conducted at the Princess Alexandra Hospital by Mater Researcher and Haematologist Professor Maher Gandhi a 46-year-old patient has been successfully cured of a rare type of lymphoma. The patient was diagnosed with brain lymphoma, a form of blood cancer confined to the brain, following a […]

“The pancreas,” says Gary Lewis, an endocrinologist at Toronto General Hospital and director of the Banting & Best Diabetes Centre at the University of Toronto’s Temerty Faculty of Medicine, “is like an exquisitely sensitive and perfectly networked computer.” Second by second, he notes, the pancreas secretes just the right amount of […]

A good way to find out what a cell is doing—whether it is growing out of control as in cancers, or is under the control of an invading virus, or is simply going about the routine business of a healthy cell—is to look at its gene expression. Though a vast […]

Children hospitalized with breathing problems due to a common viral lung infection are likely to get sicker and remain hospitalized if they have high levels of defective copies of the virus, according to a new study by researchers at Washington University School of Medicine in St. Louis. The findings, published […]

If you could stay forever young, you would probably use that opportunity. Scientists say that aging is actually a disease and should be dealt with as such. Researchers from the University of Waterloo found that there is a best time of day to take anti-aging supplements and it actually depends […]

COVID-19 stays with you even after the negative diagnosis. Some symptoms are long-lasting and can significantly alter one’s quality of life. Scientists are researching this phenomenon, called long COVID, and found that it is more common in women under 50 and people who experienced severe disease. Furthermore, this research led […]

The humble lab mouse has provided invaluable clues to understanding diseases ranging from cancer to diabetes to COVID-19. But when it comes to psychiatric conditions, the lab mouse has been sidelined, its rodent mind considered too different from that of humans to provide much insight into mental illness. A new […]

Scientists are struggling with public misconceptions on what embryoids are and what research on them entails, the confusion that leads to policy decisions restricting access to important scientific exploration, according to a new paper by experts at Rice University — who blame the use of terms like synthetic or artificial […]

A couple of years ago, Joseph Shrager, MD, professor of cardiothoracic surgery at Stanford School of Medicine, noticed a statistical anomaly in his practice. It seemed that patients were diagnosed with lung cancer at a surprisingly higher rate at 65 years old than, say, at 64 or 66. “There were no reason […]

A new analysis of the entire genetic makeup of more than 53,000 people offers a bonanza of valuable insights into heart, lung, blood and sleep disorders, paving the way for new and better ways to treat and prevent some of the most common causes of disability and death. The analysis […]

A team of researchers at the University of Alberta has uncovered a long-sought link in the battle to control cholesterol and heart disease. The protein that interferes with low-density lipoprotein (LDL) receptors that clear “bad” cholesterol from the blood was identified in findings recently published in Nature Communications by Dawei Zhang, associate professor of pediatrics […]

Over evolutionary time scales, a single gene may acquire different roles in diverging species. However, revealing the multiple hidden roles of a gene was not possible before genome editing came along. Cold Spring Harbor Laboratory scientists Zach Lippman and Anat Hendelman collaborated with Idan Efroni of Hebrew University in Israel to reveal […]

COVID-19 vaccine is what will pull us out of this pandemic. However, some people are not sure about the timing. If you are waiting for an elective surgery, should you get a vaccine shot before the procedure? Or should you wait and get the jab after the surgery? Scientists at […]

Idiopathic intracranial hypertension (IIH) increases intracranial pressure around the brain and causes blindness. Scientists are not sure what causes IIH, because the pressure builds up without the presence of tumour or disease. As the mechanism is unknown treatment for IIH is not yet developed. But now researchers at the University […]

Cocoa is delicious, warming and cosy, but it can also be healthy. Scientists at the University of Birmingham found that drinking cocoa can actually benefit you, despite its desert-like character. Researchers found that consumption of cocoa could protect people from mental stress-induced cardiovascular events – it might be life saving. […]

Triple-negative breast cancer cells engage in a “glutamine steal” — outcompeting T cells for the nutrient glutamine and impairing their ability to kill tumor cells, Vanderbilt researchers have discovered. The team found that an inhibitor of glutamine transport selectively targeted tumor cells and enhanced the antitumor immune response, suggesting it […]

While deadly, gliosarcomas are a rare central nervous system tumor often overshadowed in research by more common tumors. These sarcomas can occur either in the brain or the spine (the latter is much less common). A team of Yale researchers saw an opportunity to expand on the limited knowledge available […]

Tooth pain has been notoriously difficult to study. But now, researchers at Harvard Medical School and Massachusetts General Hospital report in a study published in Science Advances that they have uncovered a new function for odontoblasts. These cells form dentin, the shell beneath the tooth’s enamel that encases the soft dental […]

Cancer starts with mutations in a cell’s DNA, but new UC San Francisco research shows that the endurance of a tumour relies on its ability to rapidly evolve and adapt to challenges brought about by the environment in which it grows. “A major obstacle cancer cells must overcome is their […]

When someone is sick, it’s natural to want to stay as far from them as possible. It turns out this is also true for mice, according to an MIT study that also identified the brain circuit responsible for this distancing behaviour. In a study that explores how otherwise powerful instincts […]

Bipolar disorder affects millions of Americans, causing dramatic swings in mood and, in some people, additional effects such as memory problems. While bipolar disorder is linked to many genes, each one making small contributions to the disease, scientists don’t know just how those genes ultimately give rise to the disorder’s […]