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In an achievement that has significant implications for research, medicine, and industry, UC San Francisco scientists have genetically reprogrammed the human immune cells known as T cells without using viruses to insert DNA. The researchers said they expect their technique – a rapid, versatile, and economical approach employing CRISPR gene-editing […]

A University of Southampton eye expert is leading research using state-of-the art imaging to predict which patients with early age-related-macular-degeneration (AMD) are at more risk of blindness. Professor of Ophthalmology in the University’s Faculty of Medicine and Institute for Life Sciences member, Andrew Lotery, is leading an international research team which […]

Researchers have made a breakthrough in more precisely targeting drugs to cancers. Using ultrasound and lipid drug carriers (liposomes), a multi-disciplinary team of biomedical engineers, oncologists, radiologists and anaesthetists at the University of Oxford have developed a new way to improve the targeting of cancer drugs to tumours. The new […]

Travel by airplane has opened the door to experiencing different cultures and exploring natural wonders. That is, if you can get past the jet lag. But what if you could take control of the brain’s daily timing system? Biologists at Washington University in St. Louis unlocked a cure for jet […]

Injecting senescent cells into young mice results in a loss of health and function but treating the mice with a combination of two existing drugs cleared the senescent cells from tissues and restored physical function. The drugs also extended both life span and health span in naturally aging mice, according […]

A new study led by researchers at Harvard Medical School and the Harvard T.H. Chan School of Public Health has identified some of the first known inherited genetic variants that significantly raise a person’s likelihood of developing clonal hematopoiesis, an age-related white blood cell condition linked with higher risk of […]

A unique gaming system called ‘OrbIT’ will play a lead role in the fight to improve life for individuals living with Parkinson’s disease, thanks to funding from the Estate of the late Olga Mabel Woolger. In a three-year $90,000 study, Flinders University Rehabilitation Engineer, Mr David Hobbs and University of […]

New research from South Australian scientists has shown that vitamin D (also commonly known as the sunshine vitamin) is unlikely to protect individuals from multiple sclerosis, Parkinson’s disease, Alzheimer’s disease or other brain-related disorders. The findings, released in the science journal Nutritional Neuroscience reported that researchers had failed to find solid clinical […]

The study compares traditional detection of prostate cancer with a novel practice using a blood test, the Stockholm3 test, in combination with magnetic resonance imaging (MRI) and targeted prostate biopsies. More men get a correct diagnosis and treatment The results show that the suggested diagnostic strategy decreased the number of […]

Men with advanced cancer are 30 percent less likely than women to consider palliative care, according to a University of Rochester Medical Center study. Researchers believe the findings reflect social norms about gender roles — as well as widespread messages in the media and society about “fighting” cancer. Often men see themselves […]

Dementia is a hugely debilitating condition, taking its toll on aging people and their families. Humans value their intellectual ability highly and coming to terms that they are deteriorating is very difficult. Many people believe that there are some remedies that can prevent multiple sclerosis, Parkinson’s disease, Alzheimer’s disease or […]

A new study of prostate cancer in 202 men, whose cancers had spread and were resistant to standard treatment, found that a surprisingly large number of these cancers – about 17 percent – belong to a deadlier subtype of metastatic prostate cancer. Previously, it was thought that these cancers constituted […]

A typically developing 2-month-old baby can make cooing sounds, suck on her hand to calm down and smile at people. At that age, the mouth is the primary focus: Such young infants aren’t yet reaching for objects with their hands or using their feet to get around, so the lips […]

Activation of a single type of neuron appears to trigger hot-flash-like symptoms in mice.  In the issue of Cell Reports, researchers show that so-called Kiss1 neurons in the hypothalamus may be the link between sex hormone fluctuations and the hot flashes that affect many menopausal women. These cells project to a brain region controlling […]

The study, led by Imperial College London and researchers from the Universities of Bristol and Cambridge, also suggest pregnant women who develop high blood pressure (pre-eclampsia), or fetal growth restriction (where a baby's growth slows or stops before birth), may have differences in their blood circulation. The team tracked the […]

One of biology’s great mysteries is how a single fertilised egg can generate millions of cells that together make up a human body, while simultaneously restricting growth to prevent lethal diseases such as cancer. This process is strictly regulated by our DNA, the genetic cookbook carried by each single cell […]

Through x-ray crystallography and kinase-inhibitor specificity profiling, University of California San Diego School of Medicine researchers, in collaboration with researchers at Peking University and Zhejiang University, reveal that curcumin, a natural occurring chemical compound found in the spice turmeric, binds to the kinase enzyme dual-specificity tyrosine-regulated kinase 2 (DYRK2) at […]

A very low carbohydrate, high-fat diet called the ketogenic diet may improve the effectiveness of an emerging class of cancer drugs, according to a study in mice by investigators at Weill Cornell Medicine, Columbia University Irving Medical Center and NewYork-Presbyterian. In a study published in Nature, scientists provide a possible […]

Growing miniature tumors from a patient’s cells in the laboratory may help scientists personalize treatments for those with a rare form of prostate cancer, according a study by Weill Cornell Medicine and NewYork-Presbyterian scientists. Patients with prostate cancer often receive therapies that reduce levels of testosterone. Many of their tumors […]

Young women with high body fat have a decreased chance of developing breast cancer before menopause, according to scientists at the National Institutes of Health and their collaborators. The finding, published online in the journal JAMA Oncology, may help researchers better understand the role obesity plays in breast cancer risk. […]

A small-molecule drug is one of the first to preserve hearing in a mouse model of an inherited form of progressive human deafness, report investigators at the University of Iowa, Iowa City, and the National Institutes of Health’s National Institute on Deafness and Other Communication Disorders (NIDCD). The study, which […]

Gene therapy has gained momentum in the past year, following the federal government’s approval of the first such treatments for inherited retinal diseases and hard-to-treat leukemia. Now, research led by Washington University School of Medicine in St. Louis has shown, in mice, that genetic material can be delivered to damaged […]

UCLA-led team created a model to predict effectiveness of potential treatments to help the immune system. A research team led by a UCLA bioengineer has developed a model to predict the extent to which new laboratory-designed antibodies will be able to combat specific human diseases. This is the first time […]

Experiments using parasitic worms in the mouse gut have revealed a surprising new form of wound repair, a finding that could help scientists develop ways to enhance the body’s natural healing abilities. Researchers have long believed that adult stem cells contribute to wound healing in tissues like the gut and […]

Recent leaps in gene editing technology have brought ideas that just a decade ago seemed like science fiction to the cusp of reality. The already famous CRISPR system allows scientists to edit faulty genes by cutting and replacing sections of DNA, but new and improved CRISPR techniques have expanded CRISPR’s […]

Medicine is rapidly approaching a great advance that will augment or replace drugs with human cells for treating a range of intractable conditions, an expert in cell therapy told the Wisconsin Technology Council. Jacques Galipeau, assistant dean for therapeutics discovery at the University of Wisconsin School of Medicine and Public […]

This migration of cells can lead to metastatic disease, which causes about 90 percent of cancer deaths from solid tumors — masses of cells that grow in organs such as the breast, prostate or colon. Understanding the drivers of metastasis could lead to new treatments aimed at blocking the process […]

Eisai Co., Ltd. and Biogen Inc. (NASDAQ: BIIB) announced positive topline results from the Phase II study with BAN2401, an anti-amyloid beta protofibril antibody, in 856 patients with early Alzheimer's disease. The study achieved statistical significance on key predefined endpoints evaluating efficacy at 18 months on slowing progression in Alzheimer's […]

University of Adelaide research shows that the results of the most widely used test for prostate cancer may be affected by obesity. With increasing prevalence of obesity in high-income countries, this study published by the Society for Endocrinology, has important implications for detecting and monitoring the most common form of cancer […]

A device under development at the Department of Energy’s SLAC National Accelerator Laboratory and Stanford University could help bring back lost brain function by measuring how the brain responds to therapies that stimulate it with electric current. The approach could open new avenues for treating brain disorders and selectively switching […]