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Excess sugar in the blood, the central feature of diabetes, can react with immune proteins to cause myriad changes in the immune system, including inflammatory changes that promote atherosclerosis, according to a new study from scientists at Weill Cornell Medicine and University of Massachusetts Medical School. The study, published in […]

Radiation therapy appears to increase the expression of genes with mutations that induce an immune response to malignant cells, according to preclinical research by Weill Cornell Medicine and NewYork-Presbyterian investigators. The findings suggest that radiation treatment directed to tumors in mice may help to improve a form of immunotherapy that […]

Next time you reward a child with a treat, consider offering fruit, nuts or a cereal bar instead of ice cream or candy, a Cornell economist suggests. Research by an international team including Michèle Belot, professor in the Department of Economics, found that children valued a sweet food more after receiving […]

Supplementation of cocoa powder in the diet of high-fat-fed mice with liver disease markedly reduced the severity of their condition, according to a new study by Penn State researchers, who suggest the results have implications for people. Cocoa powder, a popular food ingredient most commonly used in the production of […]

In the journal “Nature Communications”, scientists of the German Center for Neurodegenerative Diseases (DZNE) report new findings on the mechanisms of “Niemann-Pick type C disease” (NPC). This rare brain disorder mainly manifests in childhood and includes severe neurological and psychiatric symptoms. Researchers led by Dr. Sabina Tahirovic have now found […]

More than 20 years after the launch of a landmark clinical trial, follow-up examinations and analyses found that not all patients with elevated eye pressure need pressure-lowering treatment to prevent vision loss from glaucoma. When the study was launched, it was universally accepted that all patients with elevated eye pressure […]

A new study investigates a genetic culprit behind abdominal aortic aneurysm, a serious condition that puts people at risk of their aorta rupturing – a potentially deadly event. Finding a viable genetic target for AAA could change the game, says senior author Katherine Gallagher, M.D., a vascular surgeon and an associate professor of […]

More than half of cervical cancer cases in the United States occur in women who have not had timely Pap smears and/or HPV tests — screenings that allow for detection of precancerous or cancerous cells on the cervix. Encouraging low-income women, in particular, to participate in such screenings likely would […]

A new study from Cold Spring Harbor Laboratory (CSHL) Research Investigator Katharina Schmack and Adjunct Professor Adam Kepecs uncovered how hallucinations are produced in human and mouse brains. Their new mouse model for hallucination-like behaviours should help uncover mechanisms and treatments for schizophrenia. Schmack was working as a psychiatrist at the Charité–Universitätsmedizin Berlin […]

For a while now, heart disease researchers have known that a protein called GRK5 – expressed throughout the body, though most notably in the lungs, heart, and placenta – normally dwells in the outer membrane of heart cells and, upon exposure to stress, moves into the cell nucleus, switching on […]

The results of this epidemiological study suggest that suffering from untreated sleep apnea can raise the risk of later dementia and mild cognitive impairment by 20-30%. How the repeated hypoxia in the brain produced by sleep apnea results in a raised risk of dementia isn't understood in detail, but it […]

Researchers at the University of Alberta are looking for ways to prevent or slow cachexia, a muscle-wasting syndrome thought to cause up to a third of the 80,000 deaths related to cancer every year in Canada. By understanding the role of activin A, a growth factor that contributes to muscle […]