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A new study of fruit flies (Drosophila) uncovers an ancient and fundamental mechanism that provides details into a long-standing mystery of reproductive biology. The results, which are relevant to higher animals including humans, add to a growing body of evidence in other organisms about the role of calcium in the […]

Cancer is relentless and resilient. When a drug blocks a cancer cell’s main survival pathway, the cell avoids the obstacle by taking different pathways or detours to save itself. This tactic is called “developing resistance,” and it’s one of the key challenges researchers face when seeking effective therapeutics to combat […]

Tel Aviv University and Sheba Medical Center researchers say they have discovered why more than half of patients with metastatic melanoma do not respond to immunotherapy cancer treatments. Wielding proteomics, an innovative “protein mapping” approach, a team of researchers led by Prof. Tami Geiger, Prof. Gal Markel, and Dr. Michal Harel of TAU's Sackler School of […]

Although the number of women being diagnosed and dying of ovarian cancer is declining, recurrence, drug resistance and mortality remain high for women with high-grade serous ovarian carcinoma, the most common form of epithelial ovarian cancer. A new study in the journal eLife by University of California San Diego School of Medicine […]

Bioengineers and biologists at the University of California San Diego have developed a method to significantly extend the life of gene circuits used to instruct microbes to do things such as produce and deliver drugs, break down chemicals and serve as environmental sensors. Most of the circuits that synthetic biologists […]

The physical activity guidelines issued today by the four Chief Medical Officers (CMOs) of England, Scotland, Wales and Northern Ireland, offer advice to all age groups and – for the first time – pregnant women, new mums and disabled adults. Drawing on the most up-to-date scientific evidence for the benefits of physical activity, […]

Chronic conductive hearing loss, a condition that can result from middle-ear infections, may interfere with  speech recognition deficits, according to the results of a new study led by Harvard Medical School scientists at Massachusetts Eye and Ear and published in the journal Ear and Hearing. This  finding suggests that not properly […]

Newborns whose mothers spent more than one week on bedrest had poorer health outcomes, according to a new study out of the University of Alberta that further challenges beliefs about pregnancy and activity levels. A team led by cardiovascular health researcher Margie Davenport conducted a review of every available randomized controlled trial of prenatal […]

Much research has pointed to how an unhealthy diet correlates to obesity, but has not explored how diet can bring about neurological changes in the brain. A recent Yale study has discovered that high-fat diets contribute to irregularities in the hypothalamus region of the brain, which regulates body weight homeostasis […]

Glycans, or complex sugars, cover the surfaces of our cells and play a key role in biological processes ranging from interacting with other cells to recognizing and fighting pathogens. With cancer, for example, they mediate the mechanisms controlling cell division, growth and mobility that affect tumor development. Glycans are ubiquitous, but […]

Rheumatoid arthritis, vasculitis and other inflammatory autoimmune diseases have a huge impact on patients’ quality of life. Autoimmune diseases, characterized by the immune system attacking the body, affect 5 to 10% of the global population. Women are affected more usually than men. It is treatable, but autoimmune disease is incurable. […]

Researchers at IMDEA Nanociencia investigate the efficiency of gold nanoclusters as drug carriers against cancer cells. Chemotherapy is one of the most used treatments against cancer, together with surgery and radiotherapy. In a chemotherapy treatment, one or several drugs are administered to the patient to remove or damage cancer cells. […]