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Every 12 minutes, someone in the United States dies of pancreatic cancer, which is often diagnosed late, spreads rapidly and has a five-year survival rate at approximately 10 percent. Treatment may involve radiation, surgery and chemotherapy, though often the cancer becomes resistant to drugs. Researchers at University of California San […]

Bioengineers at the University of California San Diego and San Diego State University have discovered a key feature that allows cancer cells to break from typical cell behavior and migrate away from the stiffer tissue in a tumor, shedding light on the process of metastasis and offering possible new targets […]

A gene therapy for chronic pain could offer a safer, non-addictive alternative to opioids. Researchers at the University of California San Diego developed the new therapy, which works by temporarily repressing a gene involved in sensing pain. It increased pain tolerance in mice, lowered their sensitivity to pain and provided […]

For certain blood cancers, such as acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), deciding whether patients need an aggressive treatment typically hinges on a set of lab tests to identify genetic changes. Some of these tests rely on technology that was invented more than 60 years ago and has […]

Eating is a dangerous business. Naturally occurring toxins in food and potentially harmful foodborne microbes can do a number on our intestines, leading to repeated minor injuries. In healthy people, such damage typically heals in a day or two. But in people with Crohn’s disease, the wounds fester, causing abdominal […]

In response to brain injury, neural stem cells cluster and migrate to the site of injury. The clustering is key – without it, the cells don’t travel. But what causes it? To investigate, Yale researchers created a 3-D model of the brain’s workings. The results of the study, led by […]

Scientists at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have identified the specialized environment, known as a niche, in the bone marrow where new bone and immune cells are produced. The study, published in Nature, also shows that movement-induced stimulation is required for the maintenance of this niche, […]

The new material, which the Advanced Photon Source helped characterize, is strong yet stretchable, and could be ideal for creating artificial tendons and ligaments for prosthetics and robotics. A research team led by the University of California, Los Angeles (UCLA) has developed a new method to make synthetic biomaterials that […]

A team led by scientists at the National Eye Institute (NEI) has noninvasively visualized the light-sensing cells in the back of the eye, known as photoreceptors, in greater detail than ever before. Published in Optica, the researchers report how they improved imaging resolution by a third by selectively blocking the […]

First of its kind study reveals dynamic interactions between dendritic growth and synaptic connectivity in the brain cells of developing mice. A little competition is never a bad thing, especially when it comes to fledging neurons growing in the brain, finds a new Stanford University study. In a first of […]

Scientists at the Case Western Reserve University School of Medicine have determined the structure of protein “fibrils” linked to Lou Gehrig’s disease and other neurodegenerative disorders—findings that provide clues to how toxic proteins clump and spread between nerve cells in the brain. Their results may also lead to developing drugs […]

Results published to show it is possible to identify Parkinson’s Disease based on compounds found on the surface of the skin. The findings offer hope that a pioneering new test could be developed to diagnose the degenerative condition through a simple and painless skin swab. Scientists at The University of Manchester […]