Related Science News

A class of experimental cancer drugs called BET inhibitors have shown promise for treating cancers of the blood but can induce toxic side effects. Now Yale researchers have found a new inhibitor that in animal studies demonstrates greater potency against a wider variety of cancers, as well as against solid […]

Cardiovascular disease is often the result of blood vessels becoming clogged by plaques—buildups of fat, calcium, and other substances that may restrict blood flow. Not every plaque is created equal, however; some are more likely to induce a heart attack or stroke than others. Now a new three-dimensional imaging technique […]

According to a recent analysis of data from two major eye disease studies, adherence to the Mediterranean diet – high in vegetables, whole grains, fish, and olive oil – correlates with higher cognitive function. Dietary factors also seem to play a role in slowing cognitive decline. Researchers at the National […]

A study by Vanderbilt researchers has identified genomic alterations in early-stage adenocarcinomas of the lung that may indicate whether the lesions develop into aggressive tumors. The study published in the American Journal of Respiratory and Critical Care Medicine is the largest analysis of in situ and early adenocarcinomas lesions using targeted sequencing. […]

In the largest study to date of proteins related to Alzheimer’s disease, a team of researchers has identified disease-specific proteins and biological processes that could be developed into both new treatment targets and fluid biomarkers. The findings suggest that sets of proteins that regulate glucose metabolism, together with proteins related to […]

Immunotherapies have revolutionized treatment for people with a variety of cancers. But when given to those with triple-negative breast cancer (TNBC), a particularly aggressive form of the disease, less than 20% respond. “A big question in the field has been, Why are the rest not responding?” says Rumela Chakrabarti, an assistant […]

A new study identifies some of the most critical genes that may drive a rare but deadly liver cancer, providing a road map for developing drugs that target those genes. The cancer, fibrolamellar carcinoma, accounts for 1-5% of all liver cancers, and disproportionately affects children and young adults. By the […]

A pioneering study has shed new light on how a group of novel organelle-based disorders affect cells. The study led by Professor Michael Schrader from the University of Exeter, and featuring an international, multi-disciplinary team of scientists, has explored on peroxisome alterations and their contribution to the disease. Organelles are the functional units […]

A multidisciplinary team of researchers at the University of Illinois at Urbana-Champaign has developed tiny sensors that measure oxygen transport in bovine lung tissue. The study – which establishes a new framework for observing the elusive connection between lung membranes, oxygen flow and related disease – was published in the […]

Researchers trying to turn off a gene that allows cancers to spread have made a surprising U-turn. By making the gene overactive and functional in the hearts of mice, they have triggered heart cell regeneration. Since adult hearts cannot usually repair themselves once damaged, harnessing the power of this gene […]

Timing is everything. A fresh example supporting the old saying has been found in connection with the systems regulated by biological clocks. Research on circadian rhythms, our internal 24-hour patterns that affect sleep-wake and metabolic cycles, has shown that timing is key for human health. When our activities and internal […]

A new technique makes it possible to track changes in gene activity across a cell’s entire genome over time in more detail than has been possible before, researchers in Seattle report. “We hope this method will improve our understanding of normal cell physiology and as well as of cell dynamics […]