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Studying mice, scientists have shown that boosting the activity of specific immune cells in the heart after a heart attack can protect against developing heart failure, an invariably fatal condition. Patients with heart failure tire easily and become breathless from everyday activities because the heart muscle has lost the ability […]

As we age, our bodies tend to develop diseases such as heart failure, kidney failure and diabetes, and the presence of anyone disease increases the risk of developing others. A drug usually targets only one condition, largely ignoring the interconnectedness of age-related diseases and requiring patients to take multiple drugs, […]

Signs of frailty and the risks it brings could be identified in young and old people alike through a new assessment developed in a study by researchers at the Universities of Strathclyde, Manchester, Liverpool, Edinburgh, and Yale. Increasing the risk of frailty is a defining characteristic of the aging process […]

Synthetic molecules made at Berkeley Lab can be used to diagnose numerous devastating illnesses. There are currently no effective treatments for prion diseases, a family of fatal neurodegenerative conditions caused by accumulations of misfolded copies of a naturally occurring protein. But now, there is finally an effective way to test […]

Researchers Lorenzo Pasquali and Mireia Ramos-Rodríguez have published recently in Nature Genetics the results of a study on the mechanisms that cause an inflammatory response to trigger pancreatic beta-cell death, leading to the onset of Type 1 Diabetes (T1D). L. Pasquali is a Ramon y Cajal researcher at the Josep […]

People who have a certain type of bacteria in their guts may be at greater risk of developing bowel cancer. The findings will be presented by the University of Bristol researcher, Dr. Kaitlin Wade, at the 2019 NCRI Cancer Conference in Glasgow. While there is increasing evidence that the make-up […]

The development of a set of strategies for delivering genome editing complexes directly to stem cells has earned a group of innovators at Case Western Reserve University School of Medicine a first-year grant of nearly $700,000 through the National Institutes of Health (NIH) Somatic Cell Genome Editing Program. The work […]

Can scrambled eggs unscramble themselves? Well, sort of. The cytoplasm of ruptured Xenopus frog eggs spontaneously reorganizes into cell-like compartments, according to a study by researchers at the Stanford University School of Medicine. “We were gobsmacked,” said James Ferrell, MD, Ph.D., professor of chemical and systems biology and of biochemistry. “If you blend a […]

Defying the odds, an individual at high risk for early-onset Alzheimer’s disease remained dementia-free for many years beyond what was anticipated. A study funded in part by the National Institute on Aging (NIA), part of the National Institutes of Health, led researchers to suggest that a gene variant may be […]

Researchers at the University of Liverpool have made a major breakthrough in the field of cell signaling. In humans, signaling in cells normally regulates cell growth and repair. However, abnormal cell signaling contributes to many diseases, including cancer and neurodegeneration. Therefore, identifying specific proteins that control cell signaling in health […]

A protein that breast, lung and other cancers use to promote their spread – or metastasis – to the brain, has been identified by a team led by Weill Cornell Medicine and NewYork-Presbyterian investigators. The protein, CEMIP, will now be a focus of efforts to predict, prevent and treat brain […]

MIT engineers have shown that they can enhance the performance of drug-delivery nanoparticles by controlling a trait of chemical structures known as chirality — the “handedness” of the structure. Many biological molecules can come in either right-handed or left-handed forms, which are identical in composition but are mirror images of […]