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MIT engineers have developed new technology that could be used to evaluate new drugs and detect possible side effects before the drugs are tested in humans. Using a microfluidic platform that connects engineered tissues from up to 10 organs, the researchers can accurately replicate human organ interactions for weeks at […]

Cancer treatment innovations are of continued interest to medical professionals, people diagnosed with cancer and their caregivers. Recently, with support from the National Institutes of Health, a team of scientists created a kind of synthetic protein called a chimeric antigen receptor (CAR) that could increase the effectiveness of immunotherapies that […]

A progressive decline in physical function, commonly referred to as functional decline, is a strong health determinant in older people. The accumulation of chronic diseases, multimorbidity, plays a major role in functional decline and has a negative impact on quality of life. Cardiovascular and neuropsychiatric diseases are common in older […]

When it comes to colorectal cancer, many people would benefit from individually tailored screening rather than standardized population guidelines. A new risk-prediction model, built by researchers at the University of Michigan and the Fred Hutchinson Cancer Research Center (Fred Hutch) in Seattle and colleagues, assesses the impact of environment and […]

A discovery sheds light on how cancerous cells differ from healthy ones, and could lead to the development of new strategies for therapeutic intervention for difficult-to-treat cancers in the future. An international team of investigators found a “stop sign”—a modified protein researchers named a PIP-stop—inside cells that are overused by […]

The absence of a protein critical to the control of inflammation may lead to rapid and severe bone loss, according to a new University at Buffalo study. The study found that when the gene needed to produce the protein tristetraprolin (TTP) is removed from healthy mice, the animals developed the […]

Bacteria found in the small intestines of mice and humans can travel to other organs and trigger an autoimmune response, according to a new Yale study. The researchers also found that the autoimmune reaction can be suppressed with an antibiotic or vaccine designed to target the bacteria, they said. The […]

An immunotherapy drug embedded in a slow-release hydrogel invented at Rice University in collaboration with the University of Texas Health Science Center at Houston (UTHealth) appears to be highly effective at killing cancer cells. STINGel combines a new class of immunotherapy drugs called stimulator of interferon gene (STING) agonists with an injectable hydrogel that […]

One of the liveliest debates in neuroscience over the past half century surrounds whether the human brain renews itself by producing new neurons throughout life, and whether it may be possible to rejuvenate the brain by boosting its innate regenerative capacity. Now UC San Francisco scientists have shown that in […]

As we get older, it’s not uncommon to experience “senior moments,” in which we forget where we parked our car or call our children by the wrong names. And we may wonder: Are these memory lapses a normal part of aging, or do they signal the early stages of a […]

After receiving a course of antiretroviral therapy for their HIV-like infection, approximately half of a group of monkeys infused with a broadly neutralizing antibody(link is external) to HIV combined with an immune stimulatory compound suppressed the virus for six months without additional treatment, according to scientists supported in part by the National […]

Death is not a single event. It is a series of events as life fades away. Part of it happens to be rigor mortis – a period of stiffness, which makes body somewhat rigid as muscles contract and joints lose flexibility. For humans it occurs after the main event of […]