Related Science News

Sometimes cancer stays put, but often it metastasizes, spreading to new locations in the body. It has long been suspected that genetic mutations arising inside tumor cells drive this potentially devastating turn of events. Now researchers have shown for the first time that our own pre-existing genetics can promote metastasis. […]

For the first time, scientists have added microscopic tracking devices into the interior of cells, giving a peek into how development starts. For the first time, scientists have introduced minuscule tracking devices directly into the interior of mammalian cells, giving an unprecedented peek into the processes that govern the beginning […]

In a tour-de-force of cryo-electron microscopy (cryo-EM), UC San Francisco researchers have become to the first to solve the structure of a hard-working protein that helps reload neurons for repeated firing, enabling signals to be relayed along nerve pathways throughout the brain. More importantly, the scientists were able to use […]

Increased blood flow to the brain after a microscopic stroke doesn’t mean that part of the brain has recovered. At least not yet. A study in Science Advances by Rice University neuro engineers Lan Luan and her colleagues used advanced neural monitoring technology to discover a significant disconnect between how long it […]

TG4050 is being evaluated in two Phase 1 clinical trials. It combines Transgene's proprietary myvac platform with NEC's cutting-edge Artificial Intelligence (AI) capabilities to select patient-specific neoantigens – Data confirm that the prediction algorithm successfully identifies immunogenic cancer mutations, even among a large set of candidate mutations – Data will […]

MIT scientists have identified a potential new strategy for treating Fragile X syndrome, a disorder that is the leading heritable cause of intellectual disability and autism. In a study of mice, the researchers showed that inhibiting an enzyme called GSK3 alpha reversed many of the behavioral and cellular features of […]

A four-year-old girl with a severely painful, rare immune disorder received life-changing targeted therapy, following whole genome sequencing at the Garvan Institute of Medical Research. Karla, now six years old, has a rare gene variant that affects an immune ‘checkpoint’ protein, resulting in an imbalance in her immune system that […]

Many severe symptoms in Parkinson’s disease are caused by the degeneration of the brain’s dopamine neurons. Transplantation of stem cell-derived dopamine neurons to patients with Parkinson’s disease is a therapeutic approach that is getting close to clinical application. The strategy uses pluripotent stem cells that are cultured under conditions that […]

A simple blood test may help predict which people with multiple sclerosis (MS) will get worse during the following year, according to a study by researchers at Karolinska Institutet in Sweden published online in Neurology, the medical journal of the American Academy of Neurology. “In a disease like MS that […]

Childhood environment and socioeconomic status affect cognitive ability and brain development during adolescence independently of genetic factors, researchers at Karolinska Institutet report in a new study published in the journal PNAS. The study demonstrates how important the family environment is, not just during early infancy but also throughout adolescence. While […]

Scientific research has changed dramatically in the centuries since Galileo, Newton and Darwin. Whereas scientists once often toiled in isolation with homemade experiments and treatises, today collaboration is the norm. Teams of scientists now routinely pool and process reams of data gleaned from high-tech instruments. Yet as modern science has […]

For decades, scientists have explored the use of liposomes –– hollow spheres made of lipid bilayers –– to deliver chemotherapy drugs to tumor cells. But drugs can sometimes leak out of liposomes before they reach their destination, reducing the dose received by the tumor and causing side effects in healthy […]