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Most protein info ever captured from a single cell thanks to new 'nanoPOTS' technology Scientists have obtained a slew of key information about proteins, the molecular workhorses of all cells, from single human cells for the first time.The stockpile of information about proteins — the most such data ever collected […]

Correlative light-electron microscopy is being used to increase our knowledge of how platelets are made in the body and the results are challenging previously held understandings. Platelets are uniquely mammalian cells, and are the small cells of the blood that are critical for us to stop bleeding when we cut […]

The Big Question At some point in a stem cell's life, it must make an irreversible transition to develop into a particular cell type. When this happens, its nucleus begins to bustle with activity: Proteins called transcription factors latch onto the cell's DNA at specific locations (called binding sites) to […]

Known as DNA charge transport, this biochemical process was first discovered in the early 1990s by Caltech's Jacqueline Barton, the John G. Kirkwood and Arthur A. Noyes Professor of Chemistry, through chemistry experiments using synthetic DNA. Her research group then found evidence that this charge transport chemistry might be utilized by […]

Early detection has been shown to increase breast cancer survival rates, but many women avoid having their mammograms taken as often as they should because of the discomfort involved. A 2013 study found that as many as half of women who were avoiding their mammograms cited pain as the reason […]

The development of an aggressive, early-onset form of colon cancer may come down to a single missing iron atom in a key DNA repair protein, according to findings from a research collaboration between the University of Michigan Life Sciences Institute, the California Institute of Technology and the University of Southern […]

A team of researchers says it has linked sensitivity to an allergen in red meat to the buildup of plaque in the arteries of the heart. While high saturated fat levels in red meat have long been known to contribute to heart disease for people in general, the new finding […]

Although inflammation can arise from infection or injury, chronic inflammation can occur in older age due to ageing processes in the immune system. Higher levels of inflammation in older age has been linked to lower bone density, according to a new study carried out at the University of Southampton. Scientists […]

Scientists have just made an important discovery as to how cancer-targeting ‘Natural Killer’ (NK) cells are fuelled in the body, which has significant implications for related therapies. They found that glutamine – vital for making the energy that fuels tumour cell growth – is not an important fuel for making […]

More research needs to be done to understand whether CRISPR-Cas9 – molecular ‘scissors’ that make gene editing a possibility – may inadvertently increase cancer risk in cells, according to researchers from the University of Cambridge and the Karolinska Institutet. The team, led by Professor Jussi Taipale, now at the Department […]

Bioengineers may be able to use the unique mechanical properties of diseased cells, such as metastatic cancer cells, to help improve delivery of drug treatments to the targeted cells, according to a team of researchers at Penn State. Many labs around the world are developing nanoparticle-based, drug delivery systems to […]

A biomimetic nanosystem can deliver therapeutic proteins to selectively target cancerous tumors, according to a team of Penn State researchers. Using a protein toxin called gelonin from a plant found in the Himalayan mountains, the researchers caged the proteins in self-assembled metal-organic framework (MOF) nanoparticles to protect them from the […]