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Scientists at UCSF and Boston Children’s Hospital have developed a new technique for making mice with brains that combine the genetics of two different mouse strains. The authors aim to use this technique to learn more about how brain cancers form, about how genetic alterations in different parts of the […]

Since he took the reins of the Abramson Cancer Center in July 2017, there hasn’t been one day where Robert H. Vonderheide hasn’t felt a thrill. “This place is on fire,” he says. “Drugs are being approved, there are new discoveries, we are excited by all the Nature, Science, and Cell papers. People are flocking here to find […]

About 15 percent of breast cancers are classified as triple-negative, lacking receptors for estrogen, progesterone, and Her2. These cancers do not respond to targeted hormonal therapies, and they tend to be particularly aggressive, often resisting systemic chemotherapy and metastasizing to other tissues. Researchers had observed that triple-negative breast cancer (TNBC) […]

A newly developed light seeks to reduce degradation of the brain in patents with Alzheimer’s disease. The technology has been approved, a company has been founded, and clinical trials await. A dramatic breakthrough in the treatment of patients with Alzheimer’s may be underway at DTU. For 18 months, a group […]

Even though we know the benefits of physical activity, many of us would rather watch TV than exercise. The reason we avoid working out may stem from our childhood experiences. Iowa State University researchers are working to understand how the emotional connection we develop with physical activity as children influences […]

Scientists at UC San Francisco have painstakingly assembled a searchable database of normal human immunity that researchers can now use as an instant comparison group in studies of the immune system and immune dysfunction. The new open-access data tool, called the 10,000 Immunomes Project (10KIP), pieces together the results of […]

The new cell-based immunotherapy, which has not yet been tested in humans with pancreatic cancer, led to mice being completely cancer-free, including cancer cells that had already spread to the liver and lungs. Each year around 9,800 people in the UK are diagnosed with pancreatic cancer. The disease is particularly […]

An oral therapy called ibudilast significantly reduced the rate of brain tissue loss in patients with progressive multiple sclerosis (MS), according to the results of a recent phase II trial. The findings, published in the New England Journal of Medicine, support further study of the drug to determine if they might also translate […]

Car accidents, sports injuries, even too much typing and texting can injure the peripheral nerves, leaving people with numbness, tingling and weakness in their hands, arms or legs. Recovery can take months, and doctors have little to offer to speed it along. Now, researchers at Washington University School of Medicine […]

Nobody knows why some children’s backs start to curve to one side just as they hit puberty. Most children diagnosed with scoliosis, or curvature of the spine, have no known risk factors. A new study suggests that the body’s inability to fully utilize the essential dietary mineral manganese might be […]

In multiple sclerosis, a defective response of the body’s own immune system leads to brain tissue damage. Gastrointestinal microbiota could play a far greater role in the pathogenesis of the disease than previously assumed, researchers at the University of Zurich have now found. Multiple sclerosis is an autoimmune disease in […]

Researchers say they have discovered a gene mutation that slows the metabolism of sugar in the gut, giving people who have the mutation a distinct advantage over those who do not. Those with the mutation have a lower risk of diabetes, obesity, heart failure, and even death. The researchers say […]