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Scientists report in a new study that by imitating a natural process of cells, they prevented the formation of protein clumps associated with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. In lab cultures of human and yeast cells, the scientists stopped the harmful clumping of FUS proteins by exposing them […]

In a study that augurs well for the therapeutic potential of klotho – a life-extending protein hormone that a minority of people naturally produce at high levels – scientists at UC San Francisco have found that administering a fragment of the klotho protein to young, aging or impaired mice rapidly […]

A large, long-term study suggests that middle aged Americans who have vascular health risk factors, including diabetes, high blood pressure and smoking, have a greater chance of suffering from dementia later in life. The study, published in JAMA Neurology, was funded by the National Institutes of Health (NIH). “With an […]

Growing older may not have to mean growing frail. A preclinical study has revealed that brief periods of intense physical activity can be safely administered at advanced age, and that this kind of activity has the potential to reverse frailty. Published in the Journal of Gerontology A in June by […]

Attaining independence from one’s parents is an enduring theme in the lives of many organisms. Birds must fly the nest, just as mammals must wean off their mother’s milk. Now a study from Princeton researchers sheds light on a similar sort of separation drama that unfolds almost from the moment […]

Diagnosing Alzheimer’s disease and determining a patient’s prognosis is an inexact business, and that stands in the way of better personalized care and advances in treatment. A new study from The Ohio State University has identified a potential new way of confirming the disease and predicting a patient’s outlook. First, […]

Cells within an injured mouse eye can be coaxed into regenerating neurons and those new neurons appear to integrate themselves into the eye’s circuitry, new research shows. The findings potentially open the door to new treatments for eye trauma and retinal disease. The study appears in the July 26 issue […]

A new study suggests that T cells, which help the body’s immune system recognize friend from foe, may play an important role in Parkinson’s disease (PD). The study, published in the journal Nature, was supported by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes […]

When women reach “a certain age” they expect some typical symptoms that signal their journey through menopause. New research from the University of Michigan shows symptoms often cluster, and how they do so can suggest who is at risk for health problems and which women likely will experience healthy aging. […]

A stem cell-based method created by University of California, Irvine scientists can selectively target and kill cancerous tissue while preventing some of the toxic side effects of chemotherapy by treating the disease in a more localized way. Weian Zhao, associate professor of pharmaceutical sciences, and colleagues have programmed human bone […]

Scientists have successfully regenerated cells in the retina of adult mice at the University of Washington School of Medicine in Seattle. Their results raise the hope that someday it may be possible to repair retinas damaged by trauma, glaucoma and other eye diseases. Their efforts are part of the UW […]

The study, published in Neuropsychopharmacology, also shows that bipolar patients treated with lithium – the main medication for the illness – have longer telomeres (a sign of slower biological ageing) compared to bipolar disorder patients not treated with lithium. This suggests that the drug may mask the ageing effects associated with bipolar […]