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Aging or impaired brains can once again form lasting memories if an enzyme that applies the brakes too hard on a key gene is lifted, according to University of California, Irvine neurobiologists. “What we’ve discovered is that if we free up that DNA again, now the aging brain can form […]

Imagine getting a phone call asking if you’d like to take part in a study … for the next 20 years. It’s a pitch that makes telemarketing look like child’s play. So no wonder Christina Wolfson, BSc’76, MSc’78, PhD’85, a professor in the Faculty of Medicine, says that the recruitment of […]

Biomedical engineers at Case Western Reserve University are growing tracheas by coaxing cells to form three distinct tissue types after assembling them into a tube structure—without relying on scaffolding strategies currently being investigated by other groups. Successful trials and further research and development could someday allow surgeons the option of […]

Iron deficiency in the first four weeks of a piglet’s life – equivalent to roughly four months in a human infant – impairs the development of key brain structures, scientists report. The abnormalities remain even after weeks of iron supplementation begun later in life, the researchers found. The discovery, reported in the […]

We know that life is short and we want to enjoy it for as long as we can. However, aging has been associated with reduced wellbeing and health as well as increasing risk of death. There are ways to combat this inevitable destiny – a new research led by scientists […]

Detailing their findings in a study published on 12 February in the journal Nature Biotechnology, an international group of researchers had introduced a DNA nanorobot capable of traveling in the bloodstream and delivering a deathly payload to malignant tumours. “It’s a combination of diagnosing the bio-markers on the surface of […]

Despite herculean efforts, cancer remains a formidable disease, with each malignant subtype responding differently to therapeutics. One hurdle specific to treating solid tumors is a protective layer called an extracellular matrix that can prevent chemotherapeutic agents from penetrating the tumor’s core. Scientists now report results in ACS’ Chemistry of Materials showing that, […]

Women with asthma who only use short-acting asthma relievers take longer to become pregnant than other women, according to international research led by the University of Adelaide. However, the study of more than 5600 women in Australia, New Zealand, the United Kingdom and Ireland also shows that women with asthma […]

Cells are typically grown on solid materials, such as tissue culture plastic, degradable polymers and bioceramics. It is thought that the strong mechanical properties of these biomaterials are required to allow cell adhesion, an important process often controlling the behaviour of stem cells and promoting implant incorporation by surrounding tissues […]

Osteoporosis affects millions of people around the globe. It causes bones to become fragile and the bone tissue is losing density. Scientists have been trying to promote bone growth in osteoporosis for quite some time and now they thing they may have the answer. Altering structure of sugar chains on […]

The work, conducted in the laboratory of Michael Elowitz, professor of biology and bioengineering, Howard Hughes Medical Institute Investigator, and executive officer for Biological Engineering, is described in a paper in the issue of Cell. In particular, the scientists studied a key communication system called “Notch,” which is used in nearly every […]

Case Western Reserve and Cleveland Clinic are leading development of a computerized tissue-imaging program that could soon help identify which lung cancer patients are likely to face an earlier recurrence of the disease. With that information, cancer experts could more accurately determine which lung cancer patients should undergo aggressive post-surgery […]