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As you might have noticed by talking to your grandma, people start losing their hearing as they age. One third of 65 year olds report have impaired hearing. Worse still, we don’t know why that happens, although 5 genes have been identified. Now scientists from UCL and King’s College London […]

Immune system becomes weaker as you age – everyone knows that.That is why older people are more susceptible to various bacterial and viral infections. But is is the same with animals? Scientists from the University of Edinburgh conducted a long-term study with a Scottish sheep breed and found out that […]

Over 30 million people worldwide are living with Alzheimer’s disease. It is a debilitating condition, which has no known cure. It is a primary cause of dementia and with ageing population it is expected that we are going to have more and more cases of Alzheimer’s in the coming decades. […]

University of Warwick researchers have developed a superior method to describe the very earliest effects that Alzheimer’s Disease proteins have on the properties of brain cells. In the paper ‘Introduction of Tau oligomers into cortical neurons alters action potential dynamics and disrupts synaptic transmission and plasticity’ published in the journal […]

Myelodysplastic syndrome (MDS), one of the most common blood cancers, has very few treatment options. Now, researchers at Cold Spring Harbor Laboratory (CSHL) have discovered a new and promising drug target for this deadly condition. “At the moment, only a small portion of patients benefit from the standard therapy for […]

Intestinal epithelial cells (IECs) are exposed to diverse types of environmental stresses such as bacteria and toxins, but the mechanisms by which epithelial cells sense stress are not well understood. New research by the universities of Bristol, Heidelberg and the German Cancer Research Center (DKFZ) have found that Nox-ROS-ASK1-MKK3-p38 signaling […]

A new therapeutic being tested by University of Alberta researchers is showing early promise as a more effective treatment that could help nearly half of patients with Duchenne muscular dystrophy (DMD). The treatment—a cocktail of DNA-like molecules—results in dramatic regrowth of a protein called dystrophin, which acts as a support […]

Everyone is a mutant but some are prone to diverge more than others, report scientists at University of Utah Health. At birth, children typically have 70 new genetic mutations compared to their parents (out of the 6 billion letters that make both parental copies of DNA sequence). A new study published […]

Researchers believe they have identified a way to prevent type 1 diabetes by restoring the immune system’s natural balance. The approach may also prove effective for battling other autoimmune diseases such as lupus and eczema, they hope. It could also have benefits for people who have already developed diabetes: The […]

When a 9-year-old girl with anemia, breathing problems, and recurrent infections sought help for her mysterious ailments, Yale researchers and their collaborators at the National Institutes of Health sequenced her genes to pinpoint a cause. What they discovered was not only a new disease but unexpected new roles for a […]

USC scientists have surmounted a big roadblock in regenerative medicine that has so far constrained the ability to use repurposed cells to treat diseases. The researchers figured out how to reprogram cells to switch their identity much more reliably than present capabilities allow. The technique uses enzymes to untangle reprogramming […]

The way we see the world around us is the result of a marriage of two neural pathways — one shared by all vertebrates and one that evolved in mammals more recently. It has been a mystery to scientists how these two networks emerge in development to help us form […]