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A new computational approach for analyzing complex datasets shows that as disease progresses, neurons and astrocytes lose the ability to maintain homeostasis. Using an innovative computational approach to analyze vast brain cell gene expression datasets, researchers at MIT and Sorbonne Université have found that Huntington’s disease may progress to advanced […]

A new research development from The University of Manchester and The Christie NHS Foundation Trust has shown progress for developing a potential new cancer treatment using high energy electron beams. The collaborative research team have published their findings in Nature’s journal, Scientific Reports, and demonstrated that Very High Energy Electron (VHEE) beams can have […]

In recent decades, researchers have made big advances in developing new cancer medicines such as Herceptin, the targeted drug to treat women diagnosed with HER2-positive breast cancer. Yet, despite these successes, cancer remains the second leading cause of death after heart disease and nearly 90 per cent of all cancer drugs entering […]

The cocktail of beneficial bacteria passed from mother to infant through breast milk changes significantly over time and could act like a daily booster shot for infant immunity and metabolism. The research, conducted by scientists from Montreal and Guatemala and published in Frontiers in Microbiology, has important implications for infant development […]

Decades ago, blue lights helped shoppers scope out sales. Today they’re helping urologists scope out cells, specifically those of non-muscle-invasive bladder cancer. UW Medicine urologists with the Seattle Cancer Care Alliance possess a mechanism that makes the tumors glow bright pink. All the better to see them. “Seventy percent of bladder […]

Scientists have known for more than a decade that “good bacteria” from healthy intestines can treat and ward off potentially deadly intestinal infections by Clostridium difficile bacteria. Now researchers at the Perelman School of Medicine at the University of Pennsylvania have discovered that immune cells called Treg cells are crucial for the success […]

University of Alberta researchers have found that limiting the amount of fat the body releases into the bloodstream from fat cells during heart failure could help improve outcomes for patients. In a recent study published in the American Journal of Physiology, Jason Dyck, professor of paediatrics in the Faculty of Medicine & Dentistry and director […]

An international research team used the ultrabright X-rays of the Advanced Photon Source to examine neurons in the brains of schizophrenia patients. What they learned may help neurologists treat this harmful brain disorder. Schizophrenia, a chronic, neurological brain disorder, affects millions of people around the world. It causes a fracture […]

As people get older, their neural stem cells lose the ability to proliferate and produce new neurons, leading to a decline in memory function. Researchers at the University of Zurich have now discovered a mechanism linked to stem cell aging – and how the production of neurons can be reactivated. […]

NineSigma, representing a global 500 medical device company, invites proposals for technologies that can alleviate the deleterious effects of calcified coronary arteries in a manner that is both easier and safer than traditional angioplasty or atherectomy procedures. The goal of this RFP is to identify technologies, beyond those that are traditionally […]

Insomnia — trouble falling asleep, staying asleep or waking up too early — is a common condition in older adults. Sleeplessness can be exacerbated by osteoarthritis, the most common form of arthritis causing joint pain. While there are effective therapies for treating insomnia in older adults, many people cannot get […]

The blood-brain barrier prevents immune cells from circulating freely in the brain, and the breakdown of its function is a major cause of post-stroke inflammation. Now, for the first time, researchers have identified how a toxic stroke byproduct, acrolein, could activate the barrier-degrading enzyme proheparanase (proHPSE). The research group has […]