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Researchers at Karolinska Institutet have studied the incidence and regional distribution of Alzheimer’s disease biomarkers in the brains of people with Down’s syndrome. The results can bring new possibilities for earlier diagnosis and preventive treatment of dementia. The study is published in Molecular Neurodegeneration. While medical advances and improvements of […]

Immunotherapy for cancer has made great advances and many patients can now receive effective treatments that were not available ten years ago. However, there are certain types of cancer that do not respond to existing immunotherapy. A study from Karolinska Institutet in Sweden published in Proceedings of the National Academy […]

Knowing precisely where proteins are frustrated could go a long way toward making better drugs. That’s one result of a new study by Rice University scientists looking for the mechanisms that stabilize or destabilize key sections of biomolecules. Atom-scale models by Rice theorist Peter Wolynes, lead author and alumnus Mingchen Chen […]

UCI’s Center for Neural Circuit Mapping is redrawing our understanding of mechanisms underlying several common disorders. Thanks to Xiangmin Xu and his team at the UCI School of Medicine’s Center for Neural Circuit Mapping, lazy eye, Alzheimer’s and other neurological diseases could become a thing of the past. Opened earlier […]

An international research team led by UC San Francisco scientists has shown, for the first time, that gut immune cells travel to the brain during multiple sclerosis (MS) flare-ups in patients. These gut cells seem to be playing a protective role, helping drive MS symptoms back into remission. Scientists know […]

When David Zeevi and Liat Shenhav began analyzing the genomes of marine microbes, their goal was to find biological tools to combat plastic pollution in the ocean. But in the course of their study, a curious observation led them to discover something much more universal: an aspect of evolution that […]

All the cells of the body come from the same tiny clump of stem cells and share the same set of genes. But by following different patterns of activating those genes, they quickly embark towards different destinies, becoming tissues as diverse as liver, blood and brain.Tracking this process in humans—who […]

Researchers at the University of Tokyo have identified how the architecture of the cell nucleus can change gene activity in plants. This discovery reveals fundamental knowledge about genome regulation and points towards future methods for potentially manipulating the expression of many genes simultaneously. The long strands of DNA and the […]

University of Virginia Cancer Center researchers have identified a gene responsible for the spread of so-called “triple-negative” breast cancer to other parts of the body – a process called metastasis – and developed a potential way to stop it. Triple-negative breast cancer is an aggressive form of breast cancer that […]

As many as 75 percent of the women in North American experience hot flashes, and many of these women still look to hormone therapy to relieve the surge of hormones, otherwise known as vasomotor symptoms, or VMS. But new research, shared recently at the Annual North American Menopause Society Conference, shows the direction of […]

Five years ago, a Yale-led partnership launched a landmark study to identify the biomarkers, or biological indicators, of autism that could help diagnose, track, and assess treatments in patients. Since then, the Autism Biomarkers Consortium for Clinical Trials has discovered the first two biomarkers for any psychiatric disorder to be accepted into […]

Prostate cancer growth is often driven by male sex hormones called androgens. Hormone therapy is commonly administered to lower the level of androgens in the body, but relapse is common when the cancer cells develop resistance to these therapies. A multidisciplinary team of cancer researchers led by Angela Koehler, the […]