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In trout, the University of Pennsylvania School of Veterinary Medicine’s J. Oriol Sunyer and colleagues discovered that a particular type of primitive antibody is essential for fighting microbes that cause disease while preserving others that make up a healthy microbiome. While many immunologists use mouse models to conduct their research, […]

Optimeos Life Sciences, a startup founded by two Princeton University faculty members, has reached agreements with six pharmaceutical companies to develop therapeutics using a Princeton-developed drug delivery technology. The collaborations have the potential to improve the effectiveness of medications for the treatment of diseases, ranging from cancer to diabetes. Optimeos, […]

A surprising discovery about a rare form of childhood brain cancer suggests a new treatment approach for that cancer – and potentially many others. Researchers at the University of Virginia School of Medicine have determined that the supposedly simple cancer, called medulloblastoma, forms an unexpectedly intricate network to drive its […]

Materials with special electric properties can help promote bone's natural healing processes. Some materials show promise promoting bone regeneration by enhancing its natural electrical properties, according to a review in the journal Science and Technology of Advanced Materials. Some solids, including bone, enamel and quartz, form an electric field when […]

Glioblastomas are relentless, hard-to-treat, and often lethal brain tumors. Yale scientists have enlisted a most unlikely ally in efforts to treat this form of cancer — elements of the Ebola virus. “The irony is that one of the world’s deadliest viruses may be useful in treating one of the deadliest […]

An international clinical trial evaluating whether two investigational drugs can slow memory loss and cognitive decline in people in the early stages of a rare, inherited form of Alzheimer’s disease has yielded disappointing results, an initial analysis of the data has shown. However, the researchers continue to explore data from […]

Like breathing or blinking, behaviors regulated by our circadian rhythms, such as digestion and sleep-wake cycles, go unnoticed by most people. But when circadian rhythms malfunction, the result can be any one of a broad range of serious, chronic disorders, from insomnia and depression to obesity, diabetes, and bipolar disorder. […]

Altering the gut microbiome might become a therapy for improving growth during infancy in cystic fibrosis patients. The composition of the gut microbiome may make a difference in height gain in infants with cystic fibrosis during their first year of life, according to a new study. Many babies with cystic […]

As the second-leading cause of death in the United States, cancer is a public health crisis that afflicts nearly one in two people during their lifetime. Cancer is also an oppressively complex disease. Hundreds of cancer types affecting more than 70 organs have been recorded in the nation’s cancer registries—databases […]

Our microbiomes — the complex communities of microbes that live in, on and around us — are influenced by our diets, habits, environments and genes, and are known to change with age. In turn, the makeup of our microbiomes, particularly in the gut, is well-recognized for its influence on our […]

Oxford University scientist have discovered the molecular ‘first responder’ which detects disturbances in the flow of blood through the arteries, and responds by encouraging the formation of plaques which can lead to serious problems, including heart attack, stroke and even death. The study, published in the journal Nature, found that mice […]

SC scientists have developed a new tool to peer more deeply and clearly into living things, a visual advantage that saves time and helps advance medical cures. It’s the sort of foundational science that can be used to develop better diagnostics and treatments, including detecting lung cancer or damage from […]