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Women who have experienced high levels of trauma in childhood, such as abuse by a parent, are biologically older at the epigenetic cellular level in adulthood than women of the same age who have not experienced such adversity, according to a new study by UC San Francisco. Epigenetic “clocks” measure […]

UC San Francisco scientists have formed a research alliance with pharmaceutical firm Eli Lilly and Company aimed at better understanding autoimmune diseases and fostering the development of new therapies. Based on the innovative Immunoprofiler model launched at UCSF in 2015, the new initiative, called AutoImmunoprofiler, inherits the most successful aspects of […]

The brain is involved in everything in our body. When so-called neurodegenerative diseases such as Alzheimer's, ALS and multiple sclerosis attack the brain, they gradually degrade the human ability to concentrate, speak, remember and move. Despite extensive research, there is much that we still do not know about the brain. […]

Mammals and cold-blooded alligators share a common four-chamber heart structure – unique among reptiles – but that’s where the similarities end. Unlike humans and other mammals, whose hearts can fibrillate under stress, alligators have built-in antiarrhythmic protection. The findings from new research were reported in the journal Integrative Organismal Biology. […]

The relationship between DNA repair pathways and cancer cells can give scientists clues for identifying potential treatments The ongoing fight of science against cancer has made great strides, but cancer cells have not made it easy. The complexity of cancer cells and their adaptive evolutionary nature complicate the search for […]

A radioactive bone cement that’s injected into bone to provide support and local irradiation is proving to be a safer alternative to conventional radiation therapy for bone tumors, according to a study led by University of California, Irvine researchers. The study shows that this brachytherapy cement can be placed into […]

Researchers from Skoltech and their colleagues have demonstrated that nanoengineered biodegradable microcapsules can guide the development of hippocampal neurons in an in vitro experiment. The microcapsules deliver nerve growth factor, a peptide necessary for neuron growth. The paper describing this work was published in the journal Pharmaceutics. Many neurodegenerative conditions […]

Professor Martijn Nawijn, an immunologist at the University of Groningen in the Netherlands, tells Horizon Magazine about his quest to map every cell in a healthy human lung.  He says this work should help to understand more about the causes of lung disease – which is comparatively understudied – and should lead to new therapies in the next 15 to […]

Scientists reveal that high blood pressure increases lung damage risk in patients with cancer who receive bleomycin chemotherapy. Bleomycin is a drug used to treat certain cancers, such as Hodgkin lymphoma and germ cell tumors. But, bleomycin chemotherapy can cause near-fatal lung damage, a condition called bleomycin-induced lung injury. Now, […]

An international team of scientists has sequenced the genome of a capuchin monkey for the first time, uncovering new genetic clues about the evolution of their long lifespan and large brains. Published in PNAS, the work was led by the University of Calgary in Canada and involved researchers at the University […]

Statistical modeling developed by Oregon State University researchers has confirmed that changes to melanoma patients’ gut microbiome led them to respond to a type of treatment capable of providing long-term benefit. Findings were published in Science. The modeling technique invented by Andrey Morgun of the OSU College of Pharmacy and Natalia […]

A study led by researchers at the University of Minnesota Medical School found a way to detect the presence of ovarian cancer in patients using Pap test samples, normally used to detect cervical cancer. Currently, no early warning system exists for ovarian cancer, which in 2021, is estimated to kill […]