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Neonatal exposure to nicotine alters the reward circuity in the brains of newborn mice, increasing their preference for the drug in later adulthood, report researchers at University of California San Diego School of Medicine in a study published “in press” in Biological Psychiatry. A UC San Diego School of Medicine […]

Recent studies suggest that long-term sufferers of Cachexia may be in for some much needed good news. Experienced by as many as half of all cancer patients – and responsible for the deaths of around 22% – Cachexia may have met its match with new technologies on the horizon already […]

A simple slice of the finger sends a complex series of interactions between types of cells into motion. Two types of cells in particular, called macrophages and fibroblasts, work together to clean up and repair the fibers destroyed by the cut. As they do so, they influence each other, they […]

Cancer survivors Monique Russier and Tyler Rabey owe their lives to a molecule called UM-171. In 2014, on a hiking trip in the mountains of Savoie, in France, Russier came down with a high fever and started coughing. A blood test and X-ray of her lungs later revealed that the […]

Tissue engineering could transform medicine. Instead of waiting for our bodies to regrow or repair damage after an injury or disease, scientists could grow complex, fully functional tissues in a laboratory for transplantation into patients. Proteins are key to this future. In our bodies, protein signals tell cells where to […]

A new fluorescent sensor developed by researchers from the University of Adelaide can detect migrating cancer cells and could be used to target medication to stop metastasis in aggressive cancers. Metastasis – the uncontrolled migration of cancer cells which creates new tumours at different locations in the body – is […]

Most living things have a suite of genes dedicated to repairing their DNA, limiting the rate at which their genomes change through time. But scientists at Vanderbilt University and the University of Wisconsin-Madison have discovered an ancient lineage of budding yeasts that appears to have accumulated a remarkably high load […]

By the time someone gets diagnosed with diabetes — in either of its forms — the insulin-making factory inside their body has ground to a halt, or at least a slow crawl. And in people with obesity, insulin supply often struggles to keep up with demand — especially if the […]

New research from the University of Missouri identifies potential therapies for metabolic disease associated with diet and exercise. Despite countless fad diets, both obesity and metabolic diseases continue to plague communities across the U.S. Now, researchers from the University of Missouri believe that the clue to treatment might be related to estrogen […]

Environmental conditions, lifestyle choices, chemical exposure, and foodborne and airborne pathogens are among the external factors that can cause disease. In contrast, internal genetic factors can be responsible for the onset and progression of diseases ranging from degenerative neurological disorders to some cancers. A team led by Ivaylo Ivanov of […]

Scientists have identified the first chemical compounds able to inhibit and regulate CRISPR systems, which could ultimately make CRISPR gene-editing technologies more precise, efficient, and safe. To identify these compounds, the researchers developed a new platform for rapidly finding small molecules that suppress CRISPR enzymes. Sometimes referred to as “anti-CRISPRs,” […]

Gastric cancer, Q fever, Legionnaires' disease, whooping cough—though the infectious bacteria that cause these dangerous diseases are each different, they all utilize the same molecular machinery to infect human cells. Bacteria use this machinery, called a Type IV secretion system (T4SS), to inject toxic molecules into cells and also to […]