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Head and neck cancer is one of the leading causes of cancer-related deaths worldwide, and squamous cell carcinomas (HNSCC) account for the majority of these cases. In a new study, based on preclinical research and published in Molecular Cancer Therapeutics, a journal of the American Association for Cancer Research, researchers […]

Cancer immunotherapy — a treatment that better enables a patient’s own immune system to attack tumors — has shown great potential against some cancers. Yet immunotherapy doesn’t work against all tumor types, and many patients who initially respond later develop resistance and relapse. Researchers at University of California San Diego […]

From lowering your risk of obesity and cardiovascular disease to improving your concentration and overall daily performance, sleep has been proven to play a critical role in our health. In a new study, researchers at University of California San Diego School of Medicine report that sleep may also help people […]

Using stem cells to restore lost functions due to spinal cord injury (SCI) has long been an ambition of scientists and doctors. Nearly 18,000 people in the United States suffer SCIs each year, with another 294,000 persons living with an SCI, usually involving some degree of permanent paralysis or diminished […]

This open access paper expands on earlier work on cellular senescence in long-lived naked mole-rats. Individuals of this species can live as much as nine times longer than equivalently sized rodents, and are near immune to cancer. In other mammals, senescent cells accumulate with age and disrupt tissue function via […]

As of the past few years, the long-standing debate over whether moderate alcohol intake has a protective effect on health had appeared to resolve to the conclusion that the observed epidemiology is explained by socioeconomic factors, not by the metabolic effects of molecules such as polyphenols present in wine or […]

Infertility is a worldwide clinical problem for human health that affects 8 to 12 percent of couples. A new study from Washington University in St. Louis has implications for understanding some age-related aspects of male reproductive health in primates, including humans. Older male rhesus monkeys sire fewer offspring, even though […]

An analysis of a large study population here shows that glucosamine supplementation results in about a 15% reduction in mortality, a sizable effect size in the context of what is known of the effects of lifestyle choices and supplementation on aging. Glucosamine is used as an anti-inflammatory intervention, but there […]

A significant number of patients reported a deterioration in their hearing when questioned eight weeks after discharge from hospital admission for COVID-19, according to the University of Manchester audiologists, in a study supported by the NIHR Manchester Biomedical Research Centre (BRC). One hundred and twenty-one of the adults admitted to […]

More than three hundred years after Antonie van Leeuwenhoek used one of the earliest microscopes to describe human sperm as having a “tail, which, when swimming, lashes with a snakelike movement, like eels in water”, scientists have revealed this is an optical illusion. Using state-of-the-art 3D microscopy and mathematics, Dr Hermes […]

African-Americans have up to three times the risk of dying from strokes as people of European descent, yet there has been little investigation of if and how genetic variants contribute to their elevated risk. Until now. A large international team of scientists has completed the largest analysis of stroke-risk genes […]

Disruption of condensates in the neurodevelopmental disorder provides insights into how cells compartmentalize chromosomes, as well as new potential therapies. New discoveries about the disruption of condensates in the neurodevelopmental disorder Rett syndrome provide insights into how cells compartmentalize chromosomes, as well as new potential paths for therapies. Scientists have, […]