Related Science News

September 12, 2018

Mutations, Drugs Drive Cancer by Blurring Growth Signals

Genetic mutations in a form of non–small cell lung cancer (NSCLC) may drive tumor formation by blurring cells’ perception of key growth signals, according to a new laboratory study published in Science. The research, led by UC San Francisco researchers, could have important implications for understanding and ultimately targeting the defective […]
September 11, 2018

Buzzing Cancer Drugs into Malignancies in the Brain

Getting cancer drugs to permeate tumors can be tough, especially in the brain, but researchers have been using ultrasound to massage the drugs into malignancies that have taken root there. A new study details how the experimental method has overcome various barriers to treating cancers in the brain. “The blood-brain barrier is a […]
September 11, 2018

Study: Walk more to reduce heart failure risk

A new University at Buffalo study has shown for the first time that walking more can significantly lower the risk of heart failure in older women. The U.S. study of more than 137,000 postmenopausal women aged 50 to 79 is the largest and most comprehensive to date that has evaluated […]
September 10, 2018

Careful — You Are Made of 'Glass'

Ever wondered how groups of cells managed to build your tissues and organs while you were just an embryo? Using state-of-the-art techniques he developed, UC Santa Barbara researcher Otger Campàs and his group have cracked this longstanding mystery, revealing the astonishing inner workings of how embryos are physically constructed. Not only does […]
September 10, 2018

Osteoarthritis research effort works to understand cartilage development

There are more than 3 million cases of arthritis in the U.S. each year, and osteoarthritis is the most common type. In patients, cartilage — the slick surface on the ends of bones — wears away, bone rubs against bone, causing swelling and stiffness. Now Keck School of Medicine of USC […]
September 10, 2018

Chronic Diseases Driven by Metabolic Dysfunction

Much of modern Western medicine is based upon the treatment of acute, immediate harm, from physical injury to infections, from broken bones and the common cold to heart and asthma attacks. But progress in treating chronic illness, where the cause of the problem is often unknown—and, in fact, may no […]
September 7, 2018

Changes in the architecture around cancer cells can fuel their spread

UCLA researchers have found that the extracellular matrix, the dense network of proteins and carbohydrates that surround a cell, can influence how cells move within the body by regulating their sugar consumption. The study shows that acute changes in a single component of the extracellular matrix can trigger a very […]
September 7, 2018

Diseased heart muscle cells have abnormally shortened telomeres

People with a form of heart disease called cardiomyopathy have abnormally short telomeres in heart muscle cells responsible for contraction, according to a new study by researchers at the Stanford University School of Medicine. A telomere is a DNA sequence that serves as a protective cap on the ends of chromosomes. […]
September 7, 2018

Focused delivery for brain cancers

A person’s brainstem controls some of the body’s most important functions, including heart beat, respiration, blood pressure and swallowing. Tumor growth in this part of the brain is therefore twice as devastating. Not only can such a growth disrupt vital functions, but operating in this area is so risky, many […]
September 7, 2018

New clues found to understanding relapse in breast cancer

A large genomic analysis has linked certain DNA mutations to a high risk of relapse in estrogen receptor positive breast cancer, while other mutations were associated with better outcomes, according to researchers from Washington University School of Medicine in St. Louis, the Baylor College of Medicine and the University of […]
September 7, 2018

Scientists identify weak point in deadly eye melanoma

A natural plant compound exploits a newly identified Achilles’ heel in a cancer of the eye, uveal melanoma. In human cancer cells growing in the lab, the compound shuts down the overactive signaling that drives uveal melanoma cell growth, according to researchers at Washington University School of Medicine in St. […]
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