Related Science News

Experts estimate up to one third of people attending specialist memory clinics could have a condition that is commonly mistaken for early dementia. In a paper published in the journal, Brain, UK academics and clinicians have collaborated to develop a diagnostic definition of the widely recognized but poorly understood condition, Functional Cognitive Disorder (FCD).  Dr Harriet Ball from the University of Bristol, first author of the […]

The disease multiple sclerosis (MS) attacks the central nervous system and, with time, can give rise to muscle tremors and loss of balance. Researchers at Karolinska Institutet have now identified a gene, Gsta4, that protects a certain kind of cell in the brain from being destroyed. It is hoped that […]

New research supported by the National Institutes of Health delineates how two relatively common variations in a gene called KIF3A are responsible for an impaired skin barrier that allows increased water loss from the skin, promoting the development of atopic dermatitis, commonly known as eczema. This finding could lead to genetic tests […]

Today's open access research is a good companion piece to a recent paper that investigates biochemical differences between long-lived and short-lived bats. Bats are renowned for, firstly, an exceptional resistance to classes of virus that are fatal to other mammals, allowing bat populations to act as reservoirs for potentially dangerous […]

In a proof-of-principle study, researchers at the Garvan Institute of Medical Research revealed a potential therapeutic approach for targeting estrogen receptor-positive (ER+) breast cancers resistant to current therapies. By combining current gold-standard treatments with a drug that restores the activity of p53, a cancer suppressor protein, the researchers found they […]

Researchers from the Garvan Institute of Medical Research have uncovered four new subtypes of cells within triple negative breast cancer, which contain promising new therapeutic targets for the aggressive disease. Using cellular genomics, the team revealed one of the new cell types produces molecules that suppress immune cells, which may […]

Researchers at the New Jersey Institute of Technology and the Children's Hospital of Philadelphia have developed an algorithm through machine learning that helps predict sites of DNA methylation — a process that can change the activity of DNA without changing its overall structure. The algorithm can identify disease-causing mechanisms that would otherwise […]

Progress against DIPG, a fatal childhood brain tumor, is usually a game of inches. Studies that hint at even small gains are cause for celebration. That’s why researchers at the University of Michigan and their collaborators are excited about discoveries that point toward a new potential treatment approach — one […]

The results of a recent clinical trial indicate that, for older adults with advanced cancer, initiating aspirin therapy may increase their risk of disease progression and early death. Notably, the vast majority of the study participants did not previously take aspirin before age 70. The study, conducted by Harvard Medical […]

Loss of a specific enzyme increases fat metabolism and exercise endurance in mice. Sugars and fats are the primary fuels that power every cell, tissue, and organ. For most cells, sugar is the energy source of choice, but when nutrients are scarce, such as during starvation or extreme exertion, cells […]

Using state-of-the-art 3D microscopy and mathematics, Dr. Hermes Gadêlha from the University of Bristol, Dr. Gabriel Corkidi, and Dr. Alberto Darszon from the Universidad Nacional Autonoma de Mexico have reconstructed the movement of the sperm tail in 3D with high-precision. Using a high-speed camera capable of recording over 8,000 frames […]

A new insight into cell signals that control cancer growth and migration could help in the search for effective anti-cancer drugs. A McGill-led study reveals key biochemical processes that advance our understanding of colorectal cancer, the third most common cancer among Canadians. Using the CMCF beamline at the Canadian Light Source (CLS) […]