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Age related macular degeneration (AMD) is the third cause of visual impairment worldwide and the leading cause of blindness in higher income countries with aging populations. It is estimated that by 2020 196 million people will suffer AMD. Several years ago, treatment of AMD had a breakthrough with the application […]

Transplanting pancreatic islet cells into patients with diabetes is a promising alternative to the daily insulin injections that many of these patients now require. These cells could act as a bioartificial pancreas, monitoring blood glucose levels and secreting insulin when needed. For this kind of transplantation to be successful, scientists need […]

New findings by researchers at Cardiff University suggest that intensive therapy during the early stages of multiple sclerosis (MS) leads to better long-term outcomes for patients, despite it often being viewed as a riskier option than other first line treatments. Dr Emma Tallantyre, from Cardiff University’s Division of Psychological Medicine […]

A study led by researchers at Cardiff University means that more people of African descent who have treatment-resistant schizophrenia could be safely given the drug best proven to manage their symptoms. The team identified a genetic and benign cause in people of African descent for lower neutrophil levels: a condition […]

Blocking two molecular pathways that send signals inside cancer cells could stave off esophageal adenocarcinoma (EAC), the most common esophageal malignancy in the United States, according to new research from a team led by Case Western Reserve University School of Medicine. The group identified the pathways using advanced computational and […]

Researchers at Karolinska Institutet in Sweden have discovered a new and rare skeletal disease. In a study published in the journal Nature Medicine they describe the molecular mechanism of the disease, in which small RNA molecules play a role that has never before been observed in a congenital human disease. The results […]

Results from a pioneering clinical trials programme that delivered an experimental treatment directly to the brain offer hope that it may be possible to restore the cells damaged in Parkinson's. The multimillion-pound study, funded by Parkinson's UK with support from The Cure Parkinson's Trust and in association with the North […]

Scientists at the University of Virginia School of Medicine have discovered a defect in immune cells known as “killer T cells” that explains their inability to destroy cancer tumors. The researchers believe that repairing this defect could make the cells much better cancer killers. Further, they predict their discovery could be used […]

Yale researchers have developed a new way to efficiently engineer immune cells, an advance which enhances the ability to fend off cancer and other diseases, they report in the issue of the journal Nature Methods. A number of new life-saving therapies rely on reconfiguring human immune cells to act as living […]

Researchers at the Lions Eye Institute (LEI) and The University of Western Australia have pioneered a study of the world’s first and only laboratory model of a rare type of retinal disease, paving the way for new treatment pathways. Cone dystrophy with supernormal rod response (CDSRR) is an inherited disease […]

University of Queensland researchers have discovered a hidden metabolic advantage that prevents people with a specific type of dwarfism from developing type 2 diabetes or cancer. UQ Diamantina Institute researcher Dr Yash Chhabra said the findings could pave the way for new diabetes treatments for all. “We set out to understand why, unlike most […]

A five-minute workout called Inspiratory Muscle Strength Training (IMST) has been shown to lower blood pressure as much as aerobic exercise and more than some medications. Participants breathe in vigorously 30 times, five days a week, through a device that provides resistance. Preliminary findings suggest it may also boost cognitive […]