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The European Cancer Stem Cell Research Institute, based with Cardiff University, has repurposed a current cancer therapy, TRAIL, to find a new treatment for advanced cancers that are resistant to anti-hormone therapy. Up to 75% of women diagnosed with breast cancer will have a cancer driven by oestrogen signalling and […]

Recent studies indicate that infants born prematurely have a higher risk of developing heart disease later in life. Now, researchers at the University of Washington School of Medicine in Seattle have shown that, in preterm animal models, inflammation due to infection can disrupt the activity of genes crucial for normal […]

Wound healing process is something we all are familiar with. The wound fills up with blood, which coagulates and seals it. Then new cells have to rebuild what was lost. However, there are many various cells in our skin and their relation in wound healing process is only partially understood. […]

A new study on the mechanics of aging and longevity finds that fruit flies inhibited from producing the protein Sirt4 — which is also found in humans — are short-lived, while flies modified to make extra Sirt4 are long-lived. In addition, flies lacking Sirt4 display increased sensitivity to starvation, decreased fertility […]

Researchers from the University’s Institute of Translational Medicine have found an explanation for how breast cancer spreads to the lungs, which could potentially hold the key to preventing the progression of the disease. Breast cancer remains the leading cause of cancer death in women due to metastasis (the spread of a cancer […]

Cancer researchers have made great strides in developing targeted therapies that treat the specific genetic mutations underlying a patient's cancer. However, many of the most common cancer-causing genes are so central to cellular function throughout the body that they are essentially 'undruggable'. Now, researchers at UC San Francisco have found […]

Researchers at Oregon State University have taken an important step toward a more convenient, less expensive means of preserving mammalian cells for in vitro fertilization, species conservation, cell therapy and other purposes. The method is desiccation – removing water from cells – and shows promise as an alternative to cryopreservation […]

Hard to detect in its early stages, and hard to treat as it advances, lung cancer is the leading cause of cancer mortality around the world, with an estimated 1.6 million deaths each year. New treatments, however, are bettering the odds for people with non-small cell lung cancer (NSCLC), which […]

More than 400,000 Canadians aged 65 and over live with diagnosed dementia, including Alzheimer’s disease, which accounts for approximately 70 percent of cases. The cause of this degenerative brain disease is largely unknown and no effective treatment exists. The disease has a devastating effect on individuals and their families. To […]

The molecular mechanisms enabling plants to quickly adapt their rate of flower production in response to changing nutrient levels in soil have been revealed by researchers at the Sainsbury Laboratory. A team of plant scientists examined the processes through which plants are able to pass on information about the external […]

On the hunt for genes involved in regenerating critical nerve fibers called axons, biologists at the University of California San Diego came away with a surprise: The discovery of a new genetic pathway that carries hope for victims of traumatic injuries—from stroke to spinal cord damage. UC San Diego Biological […]

The study, led by Dr Gunnel Halldén and funded by the charity Pancreatic Cancer Research Fund, suggests that the new technique could potentially become a promising new treatment for patients with the aggressive disease, and could be combined with existing chemotherapy to improve chances of survival. First author Dr Stella Man […]