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Some 20 percent of breast cancer survivors will suffer from lymphedema, a potentially severe side effect of treatment that makes arms swell with lymph. The disease is often overlooked, but commercially available app-based technology now makes early detection easier, allowing for proactive treatment. The lymphedema monitoring technology originated through research […]

A number of previous studies have found that the roughly 400 olfactory genes present in the human body are sometimes expressed beyond the nose, posing an interesting question for researchers involved in the field of genetics. Now, a study published in Molecular Systems Biology has shown that patients with colon […]

A protein that normally deposits mineralized calcium in tooth enamel may also be responsible for calcium deposits in the back of the eye in people with dry age-related macular degeneration (AMD), according to a study from researchers at the National Eye Institute (NEI). This protein, amelotin, may turn out to […]

Skin is our body’s most ardent defender against pathogens and other external threats. Its outermost layer is maintained through a remarkable transformation in which skin cells swiftly convert into squames—flat, dead cells that provide a tight seal between the living portion of the skin and the world outside. “Throughout our […]

Over the past few years, biochemist John Jefferson Perry at the University of California, Riverside, has collaborated on a number of projects with Atomwise Inc., a company that uses artificial intelligence, or AI, for drug discovery. Now Perry and the company have formed a joint venture called Theia Biosciences. Perry’s collaboration with […]

How does a developing embryo, which is initially round, tell left from right? This basic process is still poorly understood. However, investigating unusual cases can help shed light on how this process occurs in animals. More than a century ago, German biologist Dr. H. C. Delsman described unusual left–right (L–R) […]

Parkinson’s disease takes a lot from its victims. Patients often notice its onset as a tremor in one of their hands. As it progresses, it can impair balance, change speech patterns, alter thinking and dramatically affect movement. There is no cure, but there are ways to improve symptoms. Researchers from […]

Researchers at the University of Georgia’s Regenerative Bioscience Center and their colleagues have found that “natural killer” white blood cells could guard against the cascade of cellular changes that lead to Parkinson’s disease and help stop its progression. Natural killer (NK) cells are white blood cells that can kill tumors without being […]

All cells, like all people, need “quiet” time to function properly, and this is particularly true of T cells, one of the immune system’s main weapons. They must be ready for activation at all times, and primed to divide more rapidly than almost any cell in the body. When T […]

Scientists discover how non-human primate ovaries age, with implications for human fertility. Due to the modern tendency to postpone childbirth until later in life, a growing number of women are experiencing issues with infertility. Infertility likely stems from age-related decline of the ovaries, but the molecular mechanisms that lead to […]

During development, cells generated from people with autism have frequent breaks in the DNA of certain genes Researchers at the Salk Institute have discovered a unique pattern of DNA damage that arises in brain cells derived from individuals with a macrocephalic form of autism spectrum disorder (ASD). The observation, published […]

A combination of two previously studied osteoarthritis drugs works better than either drug alone, Salk researchers discovered. People with osteoarthritis, or “wear and tear” arthritis, have limited treatment options: pain relievers or joint replacement surgery. Now, Salk researchers have discovered that a powerful combination of two experimental drugs reverses the […]